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| Clinical effect of Funai Jiangxiao Ointment combined with Chinese medicine diet in the treatment of impaired glucose tolerance |
| WANG Feifei |
| Department of Endocrinology, Liaocheng Hospital of Traditional Chinese Medicine, Shandong Province, Liaocheng 252000, China |
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Abstract Objective To explore the effect of Funai Jiangxiao Ointment combined with Chinese medicine diet in the treatment of impaired glucose tolerance. Methods Ninety-eight patients with impaired glucose tolerance treated in Liaocheng Traditional Chinese Medicine Hospital from June 2017 to June 2018 were selected and divided into control group and observation group by random number table method. There were 49 cases in each group. Two groups were given routine health. Control group was treated with traditional Chinese medicine diet, and observation group was treated with Funai Jiangxiao Ointment on the basis of control group. Clinical efficacy, traditional Chinese medicine syndrome score, blood glucose and blood lipid indexes (FPG, 2hPBG, HbA1c, TC, TG), inflammatory factors (IL-6, TNF-α, hs-CRP) were compared between two groups. Results Total clinical effective rate of observation group was higher than that of control group, the difference was statistically significant (P < 0.05). After treatment, traditional Chinese medicine syndrome scores of two groups were lower than those before treatment, observation group was lower than control group, the differences were statistically significant (P < 0.05). After treatment, the levels of FPG, 2hPBG, HbA1c, TC and TG in two groups were lower than those before treatment, observation group was lower than control group, the differences were statistically significant (P < 0.05). After treatment, the levels of IL-6, TNF-α and hs-CRP in two groups were lower than those before treatment, observation group was lower than control group, the differences were statistically significant (P < 0.05). Conclusion Clinical effect of Funai Jiangxiao Ointment combined with Chinese medicine diet in the treatment of impaired glucose tolerance is significant. It can significantly improve the level of blood glucose and blood lipid, regulate the inflammatory reaction, and there is no obvious adverse reaction during the treatment period, with high safety.
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[1] 梁浩，张守林.清热解郁汤联合盐酸二甲双胍片治疗糖耐量减低临床研究[J].中医学报，2016，31（4）：506-509.
[2] 赵青，屈秀娟.分析与观察二甲双胍片联合替米沙坦治疗肥胖型高血压伴糖耐量减低患者效果[J].临床医药文献电子杂志，2017，4（95）：34-35.
[3] 杨滨，王五杏，张颖，等.糖耐量低减（IGT）及其干预治疗[C].中华中医药学会第七次全国中医糖尿病学术大会，2003.
[4] 中国中医药学会内科学会消渴病专业委员会.消渴病（糖尿病）中医分期辨证与疗效评定标准[J].中国医药学报，1993，8（3）：54-55.
[5] 龚敏，李峻峰，邹丽妍，等.知柏地黄丸对糖耐量减低患者炎症因子及尿微量白蛋白的影响[J].中医临床研究，2016，8（18）：30-31.
[6] 郑筱萸.中药新药临床研究指导原则（试行）[M].北京：中国医药科技出版社，2002.
[7] 邓旭，宁实，徐丽君，等.西格列汀联合二甲双胍对糖耐量减低患者血浆 C-反应蛋白和血脂水平的影响[J].检验医学与临床，2015，12（21）：3234-3235.
[8] 朱艺平，黄盛新，黎玮，等.平衡针灸治疗成人肥胖型糖耐量减低的临床观察[J].现代生物医学进展，2016，16（34）：6694-6695.
[9] 王甜甜，谭杰军，张福利.张福利运用分消走泄法治疗糖尿病糖耐量减低经验[J].山东中医杂志，2016，35（6）：542-545.
[10] 龚光明，刘桠，张翕宇，等.基于“治未病”理论以药膳馒头为主综合干预糖尿病前期的临床观察[J].成都中医药大学学报，2018，41（2）：45-46.
[11] 张素娟，董洁，申利娜.用于治疗2型糖尿病的中药及其代谢组学研究[J].中药与临床，2018，9（6）：48-49.
[12] 蔡恩照，林燕，陈玉，等.邱英明干预糖耐量减低中医辨证思路[J].浙江中西医结合杂志，2015，25（12）：1087-1088.
[13] 谢夏南，谢伟雄，郑德玲.治未病干预脾虚痰湿型糖耐量减低研究[J].现代中西医结合杂志，2015，24（10）：1079-1080.
[14] 赵永才，宋光耀，李新胜.糖耐量减低合并高甘油三酯血症患者硫氧还原蛋白相互作用蛋白与胰岛功能的相关性研究[J].中国糖尿病杂志，2017，25（12）：1086-1087.
[15] 马一骏，李青菊，李俊，等.新确诊的2型糖尿病、糖耐量减低患者认知功能和脑白质微结构的变化及相关性[J].山东医药，2017，57（43）：8-10.
[16] 刘海逸，张欣荣，岳晓丹，等.黄连解毒汤对糖耐量减低大鼠的糖尿病延缓作用[J].国际内分泌代谢杂志，2017， 37（3）：149-150.
[17] 孙超，黄延芹，徐云生，等.糖异平治疗糖耐量减低的效果及其对糖脂代谢和氧化应激水平的影响[J].西部中医药，2018，31（5）：1-3.
[18] 李凌冰，贾大林.西格列汀联合二甲双胍对糖耐量减低患者血浆C-反应蛋白和血脂水平的影响[J].检验医学与临床，2015，12（21）：3234-3236.
[19] 储琴莉，胡军，储全根，等.基于中医认识论药膳汤粥辅助治疗糖尿病[J].中医药临床杂志，2018，30（5）：34-35. |
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