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Study on the prescription of Chinese Medical Code in the treatment of ulcerative colitis based on data mining |
LI Pengfan1 LUO Yue2 ZHANG Yuli1 WANG Xueying1 CHEN Kanjun1 GU Sizhen1 DOU Danbo1 |
1.Department of Traditional Chinese Medicine, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China; 2.Yueyang Clinical Medical College, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China |
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Abstract Objective To explore the characteristics and regularity of prescriptions for the treatment of ulcerative colitis in Chinese Medical Code. Methods Based on the traditional Chinese medicine inheritance support system, the drug frequency, drug properties and taste menstruation, association rules, prescription rules, core drug combinations in the treatment of “dysentery”, “intestinal dysentery”, “stagnation” and “diarrhea” in Chinese Medical Code were analyzed. Results Among the 341 prescriptions, 200 Chinese herbs were involved, including Radix Angelicae Sinensis, Rhizoma Coptidis, Radix Glycyrrhizae, Radix Aucklandiae, Radix Paeoniae Alba, and Poria. The drugs with neutral temperature, bitter taste and pungent taste were the most frequently used, followed by those with cold nature and sweet taste, those attributed to the spleen meridian were the highest, and those attributed to the stomach meridian were the second. The drug combinations with support ≥34 were 49 groups, the core drug combinations were 10 groups, and 5 new prescriptions were produced. Conclusion Through the traditional Chinese medicine inheritance support system, the prescription medication law of ulcerative colitis in Chinese Medical Code can be revealed to a certain extent, which is helpful to improve the curative effect of traditional Chinese medicine in the treatment of ulcerative colitis.
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