低分子肝素联合口服补液盐在临界性羊水过少中的治疗效果

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Abstract Objective To study the clinical efficacy of low molecular weight heparin combined with Oral Rehydration Salts on critical amniotic fluid oligohydramnios. Methods From October 2018 to January 2019, 68 pregnant women with amniotic fluid index (AFI) between 5-8 cm were selected for color Doppler ultrasound examination in Jinhua Municipal Central Hospital of Zhejiang Province. According to the random number table method, they were divided into the observation group (36 cases) and the control group (32 cases). The observation group was treated with Low molecular weight heparin and Oral Rehydration Salt Ⅲ and the control group was given clinical observation without treatment. The changes of AFI and ratio of end systolic peak/end diastolic peak (S/D) in the two groups were observed after treatment for 7 d. Natural delivery rate, full-term birth rate, the incidence of neonatal asphyxia and postpartum hemorrhage in the two groups were counted. Results AFI values of the observation group after treatment were higher than those of the control group, S/D values were lower than those of the control group, and AFI values of the observation group were higher than those of the control group, S/D values were lower than those of the control group, and the differences were statistically significant (all P < 0.05). AFI and S/D values in the control group were not significantly different from those before treatment （P > 0.05）. The rates of spontaneous vaginal delivery and term delivery in the treatment group were higher than those in the control group, and the differences were statistically significant（P < 0.05）. There were no statistically significant differences in the incidence of neonatal asphyxia and postpartum hemorrhage between the two groups （P > 0.05）. Conclusion The Low molecular weight heparin combined with Oral Rehydration Salts has efficacy on critical amniotic fluid oligohydramnios.

Key words： Oral Rehydration Salt Critical amniotic fluid oligohydramnios Low molecular weight heparin Hydration

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	CUI Dawei FAN Xufei LYU Ying JI Limei ZHENG Xiujuan HU Min

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CUI Dawei FAN Xufei LYU Ying JI Limei ZHENG Xiujuan HU Min. Clinical efficacy of Low molecular weight heparin combined with Oral Rehydration salts on critical amniotic fluid oligohydramnios[J]. 中国医药导报, 2020, 17(18): 115-117,122.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2020/V17/I18/115

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