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| Research progress of circulating miRNA in the treatment and prognosis of hepatocellular carcinoma |
| YANG Yibo YU Baoping |
| Department of Gastroenterology, Renmin Hospital of Wuhan University, Hubei Province, Wuhan 430060, China |
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Abstract Hepatocellular carcinoma (HCC) was one of the common malignant tumors with a high mortality rate. Early and effective diagnosis of HCC was essential. MicroRNA (miRNA) was involved in the proliferation, differentiation, migration, neovascularization, apoptosis and other activities of liver cancer cells, which was expected to become new biomarkers to assist in the diagnosis, treatment and prognosis of liver cancer. This article mainly reviews the research progress of serum or plasma miRNA in the clinical application of liver cancer, and aimed to provide new ideas for the clinical diagnosis, treatment and evaluation of liver cancer prognosis.
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