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Research and application of traditional Chinese medicine for thyroid diseases based on systems biology omics technology |
MU Yafeng1 XIANG Nan2,3,4 ZENG Mingxing5 TAN Zhangkui1 CHEN Jidong2,3,4 ZUO Xinhe2,3,4 ZHAO Yong3,4 |
1.Clinical College of Traditional Chinese Medicine, Hubei University of Chinese Medicine, Hubei Province, Wuhan 430061, China;
2.the First Clinical College, Hubei University of Chinese Medicine, Hubei Province, Wuhan 430061, China;
3.Center for Diagnosis and Treatment of Thyroid Disease, Hubei Provincial Hospital of Traditional Chinese Medical, Hubei Province, Wuhan 430074, China;
4.Chen′s Academic Schools Studio of “Ying Disease”, Hubei Province, Wuhan 430061, China;
5.School of Basic Medicine, Hubei University of Chinese Medicine, Hubei Province, Wuhan 430065, China |
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Abstract Traditional Chinese medicine has unique advantages in treating thyroid diseases, especially in shortening the onset time, rapidly relieving symptoms, enhancing the efficacy of Western medicine, and reducing the toxic and side effects of Western medicine. However, the current research lacks innovation and characteristics of traditional Chinese medicine. Systems biology is a large science characterized by holistic research, which is similar to wholism concept of traditional Chinese medicine. This paper expounds the current situation of traditional Chinese medicine research on genomics, transcriptomics, proteomics and metabolomics of thyroid diseases, and puts forward the assumption and prospect of thyroid disease research from the perspective of omics technology. The omics technology based on the systems biology platform can be integrated with each other and applied to the research of traditional Chinese medicine, which can further broaden the research thought of traditional Chinese medicine for thyroid diseases.
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