|
|
Optimizating roasted technology of Aucklandiae Radix based on multi-index evaluation |
CHEN Juan1 LI Yuehui1 WANG Yin1 PENG Yu1 PENG Jun1 PENG Yanmei2 XIAO Dehua1 |
1.Hu′nan Institute of Traditional Chinese Medicine, Hu′nan Province, Changsha 410006, China;
2.Hu′nan Province Engineering Research Center for Quality Evaluation and Traceability of Traditional Chinese Medicine Preparations, Hu′nan Province, Changsha 410006, China |
|
|
Abstract Objective To optimize the processing technology of roasted Aucklandiae Radix by multi index comprehensive score combined with box-behnken design (BBD) response surface methodology. Methods The appearance character, volatile oil, costunolide and dehydrocostuslactone of the roasted Aucklandiae Radix were taking as the comprehensive evaluation indexes. The BBD response surface method was used to investigate the number of tile layers, paper simmering temperature and paper simmering time, select the best processing parameters, and verify the optimized processing process. Results The optimal processing technology of roasted Aucklandiae Radix was as follows:the wet Aucklandiae Radix was wrapped with a layer of straw paper, laying them in five layers at intervals, place them in a 100℃ oven and bake them for about 2 hours, and taking them out when they present brown. Conclusion The optimized processing technology of the paper-roasted Aucklandiae Radix is simple, feasible and stable, which can provide a basis for the setting of processing technology and standard specifications of the paper-roasted Aucklandiae Radix.
|
|
|
|
|
[1] 张南平,余坤子,康帅,等.《神农本草经》等古代本草中木香基原考证[J].中国药事,2019,33(2):172-176.
[2] 钱伟,徐溢,王昌瑞,等.木香药材活性成分及其结构修饰研究进展[J].天然产物研究与开发,2012,24(12):1857-1865,1874.
[3] 王绪颖,贾晓斌,陈彦.木香类药材的研究进展[J].中药材,2010,33(1):153-157.
[4] 王阶,乔夕瑶,林飞,等.中药饮片发展现状及质量管理中存在的问题与分析[J].中国中药杂志,2014,39(22):4475-4478.
[5] 毕波.中药炮制对中药化学成分的影响[J].中医药临床杂志,2019,31(5):804-807.
[6] 徐珍珍,史星星,樊旭蕾,等.基于灰色关联度法和FCM算法的木香质量评价研究[J].中草药,2018,49(24):5916-5922.
[7] 王静,李艳,王芳,等.优选黄连制木香炮制工艺研究[J].亚太传统医药,2018,14(11):43-46.
[8] 曾永长,梁少瑜,吴俊洪,等.基于抗乙酰胆碱酯酶活性及多成分含量分析的天泰1号提取工艺优化[J].中药新药与临床药理,2019,30(5):602-607.
[9] 王仕宝,蔡艳妮,贾慧梅,等.HPLC法测定不同来源重楼药材中7种甾体皂苷的含量[J].西北药学杂志,2017, 32(2):133-138.
[10] 国家药典委员会.中华人民共和国药典[S].四部.北京:中国医药科技出版社,2015:374-377.
[11] 张旭,侯影,贾天柱.正交法配合药效指标综合筛选木香切制工艺[J].中国实验方剂学杂志,2011,17(7):9-12.
[12] 国家药典委员会.中华人民共和国药典[S].一部.北京:中国医药科技出版社,2015:62.
[13] 湖南省食品药品监督管理局.湖南省中药饮片炮制规范[M].长沙:湖南科学技术出版社,2010:77.
[14] 许天阳,董坤园,宋凤媛,等.Box-Behnken响应面法优化炒赤芍炮制工艺[J].中国药房,2019,30(20):2845-2850.
[15] 张旭,范冰冰,高思雨.多指标综合评价方法优选木香纸煨工艺[J].中国药师,2017,20(12):2142-2145.
[16] 宋燕,冉姗,孙方方,等.Box-Behnken设计-响应面法优化木鳖子霜炮制工艺[J].中草药,2019,50(2):382-387.
[17] 孟冉,张振凌,王胜超,等.Box-Behnken响应面法优选麸炒白芍工艺[J].中华中医药学刊,2019,37(2):357-361.
[18] 王雅莉,胡光,张倩,等.炮制对中药的化学成分及药理作用的影响[J].重庆理工大学学报:自然科学,2019,33(5):127-136.
[19] 仲锡铜,耿晖,徐瑞军.中药煨制法的现代研究[J].山东中医杂志,2002,21(9):560-561.
[20] 江川,黄玉芳,章靓,等.3种不同炮制方法对白土茯苓中β-谷甾醇含量的影响[J].中国医药科学,2019,9(23):34-37.
[21] 张雪雪,汤玉婷,唐磊,等.黄精的炮制与质量分析研究进展[J].中国现代医生,2018,56(22):165-168.
[22] 李力,张振秋.不同炮制方法对木香中有效成分含量的影响[J].华西药学杂志,2011,26(2):177-178.
[23] 文加旭,赵德,邓君.炮制方法对木香挥发油成分的影响[J].中药材,2012,35(9):1397-1401. |
|
|
|