|
|
|
| Experience of Wu Xianwen in treating radiation-induced oral mucositis by stages |
| YUE Jiajia1 WU Xianwen2 CAI Linlin2 WANG Qing1 WANG Shan1 |
1.Graduate School, Beijing University of Chinese Medicine, Beijing 100029, China;
2.Department of Oncology, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing 100091, China |
|
|
|
Abstract This paper summarizes professor Wu Xianwen’s experience in the treatment of radiation-induced oral mucositis with traditional Chinese medicine. Radiation-induced oral mucositis is an inflammation of oral mucosa caused by radiation, which is one of the common complications in radiotherapy for head and neck malignant tumors. According to many years′ working experience of radiotherapy and the treatment practice of traditional Chinese medicine, professor Wu puts forward that radiation-induced oral mucositis is caused by the heat-toxin, which would cause the stagnation of qi, invasion of blood and deficiency of yin, and its pathogenesis changes with the trend of struggle between the healthy tendency and the sick tendency. He considers that through the excessive degree of “heat, blood stasis and deficiency”, this disease can be divided into “early stage, middle stage and later stage”. While in treatment, professor Wu advocates the theory of treatment by stages, with the main treatment of heat-clarifying and blood-cooling, detoxicating and promoting blood, tonifying qi and nourishing yin. He also pays attention to the regulation of qi and blood, combination of internal and external treatment, and he is skilled in using the theory of “dispersing fire for treating depressing fire”. This unique idea of staged diagnosis and treatment has remarkable clinical effect.
|
|
|
|
|
|
[1] 谢靖，盛沛，李博，等.放射性口腔黏膜炎的发病机制及中西医防治研究进展[J].南京中医药大学学报，2019，35（3）：338-343.
[2] Trotti A，Bellm Lisa A，Epstein JB，et al. Mucositis incidence，severity and associated outcomes in patients with head and neck cancer receiving radiotherapy with or without chemotherapy：a systematic literature review [J]. Radiother Oncol，2003，66（3）：253-262.
[3] 姜德友，周岚，韩洁茹.口疮源流考[J].安徽中医药大学学报，2019，38（2）：1-4.
[4] 唐·王冰.黄帝内经素问[M].北京：人民卫生出版社，2012：279-363.
[5] 秦楚峰，王朝军，纪云西.从“阳虚阴实”探讨肿瘤之证机治要[J].中医药临床杂志，2019，31（1）：10-12.
[6] 孙铭良，王萍.“治未病”理论探析[J].内蒙古中医药，2017，36（1）：130.
[7] 王华，杜元灏.针灸学[M].北京：中国中医药出版社，2014：40.
[8] 高学敏.中药学[M].北京：中国中医药出版社，2007：97-99.
[9] 张紫薇，陈慧娟，梁尚华.升麻方药考略[J].中华中医药杂志，2019，34（2）：556-559.
[10] 齐德之.外科精义[M].盐城：江苏科学技术出版社，1985：29.
[11] 吴娇，王聪，于海川.金银花中的化学成分及其药理作用研究进展[J].中国实验方剂学杂志，2019，25（4）：225-234.
[12] 盖晓红，刘素香，任涛，等.黄连的化学成分及药理作用研究进展[J].中草药，2018，49（20）：4919-4927.
[13] 王俊壹，程海波.癌毒病机理论与“固本清源”理论辨析[J].中华中医药杂志，2019，34（10）：4687-4690.
[14] 杨丹.论同气相求与《黄帝内经》“阴阳交感”思想的关系[J].中华中医药杂志，2019，34（10）：4592-4594.
[15] 罗美.古今名医方论[M].海门：江苏科学技术出版社，1983：53-54.
[16] 孙占学，李曰庆，张丰川，等.中医外治法源流[J].中华中医药杂志，2016，31（11）：4416-4419.
[17] 吴师机.理瀹骈文[M].北京：中国中医药出版社，1995：9-10.
[18] 张颖，陈建伟，高源.九香虫资源鉴定、化学、药理与药食应用研究[J].亚太传统医药，2009，5（9）：44-47.
[19] 王靖怡，高嘉良，王阶.“火郁发之”探微[J].中医杂志，2019，60（13）：1081-1084.
[20] 李仝，张晓红.“火郁发之”的临床应用[J].中华中医药杂志，2008，23（6）：555-556.
[21] 唐元瑜，纪立金.《内经》“火郁发之”理论的发生学研究[J].辽宁中医药大学学报，2017，19（5）：79-81. |
|
|
|
