心血管病住院患者代谢综合征与ASCVD的风险因素分析

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Abstract Objective To analyze the correlation between the metabolic syndrome (MS) in hospitalized patients with cardiovascular disease and prediction for atherosclerotic cardiovascular disease (ASCVD) risk in China (China-PAR) score and the clinical data, and to explore the risk factors of ASCVD. Methods From April 2018 to March 2019, 327 patients with cardiovascular diseases who met the inclusion criteria in Xiangya Hospital Central South University were collected for medical history collection and physical examination. Patients were divided into MS group (201 cases) and non-MS group (126 cases) using the International Diabetes Federation diagnostic criteria. ASCVD risk assessment was carried out with the China-PAR model, and the patients were divided into the low-medium-risk group (188 cases) and the high-risk group (139 cases) for comparative analysis based on the score of China-PAR. Logistic regression was used for statistical analysis. Results In this study, the MS incidence rate of the patients was 61.47% (201/327). There were statistically significant differences between the MS group and the non-MS group in gender, abdominal circumference, body mass index, triglyceride, high-density lipoprotein, fasting blood glucose, systolic pressure, glycosylated hemoglobin, hypertension and diabetes history (all P ＜ 0.05). The total score of China-PAR was (9.97±6.00) scores. There were statistically significant differences in age, fasting blood glucose, glycosylated hemoglobin, systolic pressure, hypertension and diabetes history between the low-medium-risk group and the high-risk group (all P ＜ 0.05). Logistic regression analysis showed that MS (OR = 1.665, 95%CI: 1.001 to 2.770, P = 0.050), age ≥65 years (OR = 5.569, 95%CI: 3.324 to 9.330, P = 0.000) and history of alcoholism (OR = 2.348, 95%CI: 1.130 to 4.877, P = 0.022) were ASCVD risk factors. Conclusion The incidence of MS in hospitalized patients with cardiovascular disease is significantly higher than that of the general population. Inpatients with MS, old age, and alcohol abuse are risk factors of ASCVD.

Key words： Metabolic syndrome Cardiovascular disease Prediction risk Old age Risk factors

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	CAI Qiong HAN Huiwu PENG Shanshan CHEN Nengfeng XIAO Ying SHEN Lu

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CAI Qiong HAN Huiwu PENG Shanshan CHEN Nengfeng XIAO Ying SHEN Lu. Analysis of risk factors of metabolic syndrome and ASCVD in hospitalized patients with cardiovascular disease[J]. 中国医药导报, 2020, 17(14): 57-60.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2020/V17/I14/57

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