循环miRNA作为肺癌诊断和预后无创标志物的研究进展

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Abstract Lung cancer is one of the malignant tumor with the highest incidence rate and mortality rate in the world, which seriously affects human health. Despite advances in technology for lung cancer diagnosis and targeted therapy,due to the lack of accurate and effective early detection methods, the current diagnosis and prognosis of lung cancer is still not ideal, with a low survival rate. Lung cancer is regulated by a variety of mechanisms, among which microRNAs (miRNAs) participate in gene expression regulation after transcription and accompany the whole process of tumor development. Recent studies have found that abnormal expression of circulating miRNA detected in serum and plasma biological fluids is closely related to early diagnosis and prognosis of lung cancer. In this paper, the pathway, stability and potential biomarker of early diagnosis and prognosis of lung cancer are reviewed and discussed.

Key words： Circulating miRNA microRNA Lung cancer Diagnosis Prognosis

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	Articles by authors
	DU Xinyue1
	2 YANG Huiling1
	2

Cite this article:

DU Xinyue1,2 YANG Huiling1,2. Research progress of circulating miRNA as a noninvasive marker for diagnosis and prognosis of lung cancer[J]. 中国医药导报, 2020, 17(14): 31-34.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2020/V17/I14/31

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