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| Effects of depression on relapse rate and quality of life in chronic alcohol dependent patients |
| ZHAO Zhiqiang1 XIA Yeling2▲ JI Xiangping3 XU Qiong1 FU Hui1 |
1.Department of Addiction Medicine, Xinjiang Mental Health Center (Urumqi Fourth People′s Hospital), Xinjiang Uygur Autonomous Region, Urumqi 830002, China; 2.Department of Psychological Evaluation Center, Xinjiang Mental Health Center (Urumqi Fourth People′s Hospital), Xinjiang Uygur Autonomous Region, Urumqi 830002, China;
3.Department of Outpatient, Xinjiang Mental Health Center (Urumqi Fourth People′s Hospital), Xinjiang Uygur Autonomous Region, Urumqi 830002, China |
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Abstract Objective To investigate the effect of depression on the relapse rate and quality of life in chronic alcohol dependent patients. Methods From January to December 2016, a total of 275 patients diagnosed as “chronic alcohol dependence” by the Department of Addiction Medicine of Xinjiang Mental Health Center (the Fourth People′s Hospital of Urumqi) were selected. According to whether they drank again or not, they were divided into the relapse group (165 cases) and the non-relapse group (110 cases). The general situation questionnaire and Hamilton depression rating scale (HAMD) and 36-item short form health survey (SF-36) were used to measure the patients. Results The HAMD score of depression scale and the final score of SF-36 in the quality of life scale was significantly lower than that in the non-relapse group (P ＜ 0.05). There was no statistically significant difference in the final score of relapse rate and quality of life between the HAMD score < 7 and > 24 (P ＞ 0.05). The final scores of the two groups with HAMD score < 7 and 7-24 showed statistically significant differences in the rate of relapse and quality of life (P ＜ 0.05). The final scores of relapse rate and quality of life in the HAMD scores of 7-24 and ＞ 24 showed statistically significant differences (P ＜ 0.05). Conclusion Depression can lead to increased relapse rates and decreased quality of life in patients with chronic alcohol dependence. However, mild to moderate depression may have a more serious impact on the relapse rate and quality of life of patients with chronic alcohol dependence. Therefore, more attention should be paid in chronic alcohol dependent patients accompanied by mild to moderate depression in future work.
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