带状疱疹后遗神经痛的中西医治疗进展

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Abstract Postherpetic neuralgia (PHN) is the most common complication of acute herpes zoster. The persistence of pain has a substantial effect on the patients′ quality of life. At present, a variety of methods are used to treat PHN. Anticonvulsants, antidepressants, opioids and topical therapies including Lidocaine and Capsaicin are the most widely used therapies for the treatment of PHN, due to adverse effects, they should be used carefully in the elderly patients or with significant comorbidities. Nerve block, neuromodulation and other measures also play an important role in the treatment of PHN. However, the efficacy, tolerability and safety of these invasive methods should be closely monitored. Chinese medicine therapy have little side effects and significant effect for the treatment of PHN, we should be carried out individualized differentiation of symptoms and signs on the basis of types. For some PHN patients who have intractable pain and poor treatment effect, we can consider integrated traditional Chinese and Western medicine to give full play to their advantages. This paper reviews the traditional Chinese and Western medicine treatment of PHN, so as to provide reference for clinical treatment.

Key words： Postherpetic neuralgia Treatment Traditional Chinese and Western medicine

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	HUANGFU Jiaxin SHEN Dexin

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HUANGFU Jiaxin SHEN Dexin. Treatment progress on traditional Chinese and Western medicine of postherpetic neuralgia[J]. 中国医药导报, 2020, 17(12): 65-68.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2020/V17/I12/65

[1] 张学军.皮肤性病学[M].8版.北京：人民卫生出版社，2014：65.
[2] Werner RN，Nikkels AF，Marinovi■ B，et al. European consensus-based （S2k） Guideline on the Management of Herpes Zoster-guided by the European Dermatology Forum （EDF） in cooperation with the European Academy of Dermatology and Venereology （EADV），Part 1：Diagnosis [J]. J Eur Acad Dermatol Venereol，2017，31（1）：9-19.
[3] Schlereth T，Heiland A，Breimhorst M，et al. Association between pain，central sensitization and anxiety in postherpetic neuralgia [J]. Eur J Pain，2015，19（2）：193-201．
[4] Patel R，Dickenson AH. Mechanisms of the gabapentinoids and α2δ-1 calcium channel subunit in neuropathic pain [J]. Pharmacol Res Perspect，2016，4（2）：e00205.
[5] Moore RA，Wiffen PJ，Derry S，et al. Gabapentin for chronic neuropathic pain and fibromyalgia in adults [J]. Cochrane Database Syst Rev，2014，27（4）：CD007938.
[6] Ifuku M，Iseki M，Hidaka I，et al. Replacement of gabapentin with pregabalin in postherpetic neuralgia therapy [J]. Pain Med，2011，12（7）：1112-1116.
[7] Domon Y，Kitano Y，Makino M，Analgesic effects of the novel α2δ ligand mirogabalin in a rat model of spinal cord injury [J]. Pharmazie，2018，73（11）：659-661.
[8] Kato J，Matsui N，Kakehi Y，et al. Mirogabalin for the management of postherpetic neuralgia：a randomized，double-blind，placebo-controlled phase 3 study in Asian patients [J]. Pain，2019，160（5）：1175-1185.
[9] Lin YT，Lan KM，Wang LK. Treatment of postherpetic neuralgia with intravenous administration of zinc sulfate：a case report [J]. A A Pract，2018，11（1）：8-10.
[10] Baron R. Neuropathic pain：a clinical perspective [J]. Handb Exp Pharmacol，2009（194）：3-30.
[11] Vieweg WV，Wood MA. T ricyclic antidepressants，QT interval prolongation，and torsade de pointes [J]. Psychosomatics，2004，45（5）：371-377.
[12] Finnerup NB，Otto M，McQuay HJ，et al. Algorithm for neuropathic pain treatment：an evidence based proposal [J]. Pain，2005，118（3）：289-305.
[13] Raja SN，Haythornthwaite JA，Pappagallo M，et al. Opioids versus antidepressants in postherpetic neuralgia：a randomized，placebo-controlled trial [J]. Neurology，2002， 59（7）：1015-1021.
[14] Saxena AK，Nasare N，Jain S，et al. A randomized，prospective study of efficacy and safety of oral tramadol in the management of post-herpetic neuralgia in patients from north India [J]. Pain Pract，2013，13（4）：264-275.
[15] Sampathkumar P，Drage LA，Martin DP. Herpes zoster （shingles） and postherpetic neuralgia [J]. Mayo Clin Proc，2009，84（3）：274-280.
[16] Krumova EK，Zeller M，Westermann A，et al. Lidocaine patch （5%） produces a selective，but incomplete block of Aδ and C fibers [J]. Pain，2012，153（2）：273-280.
[17] Clere F，Delorme-Morin C，George B，et al. 5% lidocaine medicated plaster in elderly patients with postherpetic neuralgia：results of a compassionate use programme in France [J]. Drugs Aging，2011，28（9）：693-702．
[18] Hans G，Sabatowski R，Binder A，et al. Efficacy and tolerability of a 5 % lidocaine medicated plaster for the topical treatment of post-herpetic neuralgia：results of a long-term study [J]. Curr Med Res Opin，2009，25（5）：1295-1305.
[19] Kennedy WR，Vanhove GF，Lu SP，et al. A randomized，controlled，open-label study of the long-term effects of NGX-4010，a high-concentration capsaicin patch，on epidermal nerve fiber density and sensory function in healthy volunteers [J]. J Pain，2010，11（6）：579-587.
[20] 朱明明，刘科峰．A型肉毒毒素治疗带状疱疹后遗神经痛疗效评价[J].中国麻风皮肤病杂志，2018，34（8）：473-474．
[21] Jain P，Jain M，Jain S. Subcutaneous injection of botulinum toxin in patients with post herpetic neuralgia. A preliminary study [J]. J Assoc Physicians India，2018，66（7）：48-49.
[22] Doo AR，Choi JW，Lee JH，et al. The efficacy of selective nerve root block for the long-term outcome of postherpetic neuralgia [J]. Korean J Pain，2019，32（3）：215-222.
[23] Malec-Milewska M，Horosz B，S?誰kowska A，et al. 5% lidocaine medicated plasters vs. Sympathetic nerve blocks as a part of multimodal treatment strategy for the management of postherpetic neuralgia：a retrospective，consecutive，case-series study [J]. Neurol Neurochir Pol，2015，49（1）：24-28.
[24] Pei Q，Zhuo Z，Jing B，et al. The effects of repetitive transcranial magnetic stimulation on the whole-brain functional network of postherpetic neuralgia patients [J]. Medicine（Baltimore），2019，98（25）：e16105.
[25] Pei Q，Wu B，Tang Y. Repetitive transcranial magnetic stimulation at different frequencies for postherpetic neuralgia：a double-blind，sham-controlled，randomized trial [J]. Pain Physician，2019，22（4）：E303-E313.
[26] 薛天萍，石磊，毛丽艳.桃红四物汤加减治疗带状疱疹后遗神经痛58例[J].湖南中医杂志，2017，33（2）：58-60.
[27] 王朋军.桃红四物汤加味治疗老年带状疱疹后遗神经痛的疗效观察[J].光明中医，2014，29（12）：2562-2564.
[28] 吴家民，谭汶键，吴锦镇，等.皮肤针叩刺联合身痛逐瘀汤治疗气滞血瘀型带状疱疹后遗神经痛临床观察[J].河北中医，2018，40（2）：283-286.
[29] 陈琳，卓锦钊，姚东文.香丹止痛方联合西药治疗肝郁气滞血瘀PHN患者的疗效观察及对Th17/Treg细胞平衡的影响[J].中国中西医结合杂志，2019，39（10）：1199-1203.
[30] 季静，王和生，刘兰英.盛氏“祛瘀扶正”针法对不同性质带状疱疹后遗神经痛疗效观察[J].辽宁中医药大学学报，2016，18（12）：142-144.
[31] 冯启廷，何彬，陈小丽，等.冯氏排针法治疗带状疱疹后遗肋间神经痛疗效观察[J].实用中医药杂志，2015，31（1）：51-52.
[32] 喻杉，杨仕年，曾帅.疏肝安神针法治疗带状疱疹后遗神经痛疗效观察[J].四川中医，2014，32（4）：167-169.
[33] Li HP，Su W，Shu Y，et al. Electroacupuncture decreases Netrin-1-induced myelinated afferent fiber sprouting and neuropathic pain through μ-opioid receptors [J]. J Pain Res，2019，23（12）：1259-1268.
[34] 武彩花，毛红蓉，李洪萍，等.电针对带状疱疹后遗神经痛大鼠脊髓背角血管内皮生长因子表达的影响[J].针刺研究，2018，43（4）：203-208.