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| Mechanism of acupuncture in the treatment of allergic rhinitis |
| PENG Yongjun1 JIANG Xingzhuo1 LI Wenqian1 WU Xu1 ZHU Bingmei2 |
1.Department of Acupuncture and Moxibustion, Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province, Nanjing 210029, China;
2.Center for Regenerative Medicine, West China Hospital, Sichuan University, Sichuan Province, Chengdu 610041, China |
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Abstract Allergic rhinitis (AR) is a common non-infectious chronic inflammatory disease of the nasal mucosa mediated by immunoglobulin E (IgE) when body is exposed to allergens. Acupuncture, as a common treatment for AR, has the advantages of safety, effectiveness, and few side effects. This review summarized and discussed the progress of the pathogenesis of AR and the mechanisms of acupuncture treatment by retrieving relevant literatures in recent years. The mechanisms underlying AR are complex, including immunity disorder, nerve dysfunction, and nasal mucosal inflammatory cell infiltration. The studies showed that acupuncture can play a therapeutic role through immunoregulation, neuromodulation, decreasing IgE, and reducing nasal mucosal inflammatory infiltration. Also, the review pointed out some problems and shortcomings in the current research, and provided ideas for further study.
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