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Research on the main factors affecting the chemical composition of Eucommia ulmoides Oliv. |
LIU Kun1 PAN YingYi1 WANG Jianying2 CHENG Xiaoyun3 YUAN Ying1 |
1.School of Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China;
2.Collaborative Innovation Center, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China;
3.Department of Rheumatology, Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China |
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Abstract This article reviews the chemical composition of Eucommia ulmoides Oliv. from different medicinal parts, processing methods, producing area, collection time and serum drug metabolism. It is found that the influence of different medicinal parts of Eucommia ulmoides Oliv. on the chemical composition is mainly reflected in the great difference in the content of effective components and the representative components of each part. The influence of collection time in producing area is mainly manifested in the obvious difference of chemical composition content. The processing methods of Eucommia ulmoides Oliv. mainly changes the structure of its chemical composition and the ratio of its species. The chemical components of Eucommia ulmoides Oliv. are still prototype after drug metabolism, but the pharmacokinetic characteristics of each component are quite different. This article also combines five main influencing factors to elaborate the relevant drug effects. It may provide a reference to explain the material basis of Eucommia ulmoides Oliv. exerting different drug effects to a certain extent, and may also provide a reference for the clinical application and resource development of Eucommia ulmoides Oliv..
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