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| Risk factors analysis of peripherally inserted central catheter associated thrombosis in lung cancer patients with chemotherapy |
| YUAN Na1 WANG Lei2 WU Xueliang3 |
1.Department of Radiotherapy, First Affiliated Hospital of Hebei North University, Hebei Province, Zhangjiakou 075000, China;
2.Department of Intensive Care Unit, First Affiliated Hospital of Hebei North University, Hebei Province, Zhangjiakou 075000, China;
3.Vascular Gland Surgery, First Affiliated Hospital of Hebei North University, Hebei Province, Zhangjiakou 075000, China |
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Abstract Objective To discuss the incidence rate and risk factors of peripherally inserted central catheter (PICC) related thrombosis in patients with lung cancer receiving chemotherapy. Methods From January 2014 to January 2015, in First Affiliated Hospital of Hebei North University, 157 patients with lung cancer receiving chemotherapy and PICC were selected and observed for 180 days. The diagnosis of thrombosis was based on Doppler Sonography. Age, gender, tumor type, clinical stage, treatment,c omplications, PICC catheter selection of vein, PICC catheter time, different chemotherapy drugs and the influence of PICC related thrombosis were analyzed by single factor and the multiple Logistic regression to study. Results Among 157 caces, 17 cases (10.8%) ocurred symptomatic PICC-related thrombosis. The patients were individed into PICC-related thrombosis group and no-PICC-related thrombosis group according into thrombosis occurrence. PICC-related thrombosis group and no-PICC-related thrombosis group were compared, the differences of gender, clinical stage, using Etoposide were statistically significant (P < 0.05), the differences of the age, tumor type, treatment, complication, PICC catheter selection of vein and PICC catheter time were not statistically significant (P > 0.05). the multiple Logistic regression analysis suggested that the risk of PICC related thrombosis with patients with lung cancer receiving of etoposide treatment increased 1.373 times, the risk of PICC related thrombosis in female was 1.219 times that in male,and the risk of ⅢB-Ⅳ stages was 4.347 times that ofⅡ-ⅢA stages. Conclusion The gender, clinical stages and using Etoposide are the risk factors in lung patients with PICC-related thrombosis.
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