降钙素原、C-反应蛋白、红细胞沉降率与白细胞计数联合检测在呼吸道感染诊断中的应用价值

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Abstract Objective To explore the value of the combined detection of procalcitonin (PCT), C-reactive protein (CRP), erythrocyte sedimentation rate (ESR) and white blood cell (WBC) count in the diagnosis of respiratory tract infection. Methods From February 2018 to July 2019 in Wuhu NO.1 People′s Hospital, a total of 60 patients with respiratory tract infection were selected as experimental group. According to whether the bacterial infection, they were divided into bacterial infection group (33 cases) and non-bacterial infection group (27 cases). While another 30 healthy subjects were selected as the control group during the same period. The serum PCT, CRP, ESR and WBC count levels of each group were detected quantitatively and compared. Results In the combined detection of PCT, CRP, ESR and WBC counts, the positive rate of the bacterial infection group were significantly higher than those of the nonbacterial infection group and the control group, and the differences were statistically significant (P ＜ 0.05). The area under the ROC curve was the largest during the combined detection, followed by the WBC count, PCT, and ESR, and the CRP was the smallest. The accuracy, sensitivity, and specificity of the combined detection of all indicators were higher than those of the single detection, and the differences were statistically significant (P ＜ 0.05). Conclusion The combined quantitative detection of PCT, CRP, ESR and WBC counts has higher diagnostic value for respiratory infections. It can distinguish bacterial and non-bacterial respiratory infections, and provide a basis for clinical rational drug use.

Key words： Procalcitonin C-reactive protein Erythrocyte sedimentation rate White blood cell count Respiratory infection

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	CAO Jinjin CUI Fan LIU Furong XU Chengquan QIAN Zengkun

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CAO Jinjin CUI Fan LIU Furong XU Chengquan QIAN Zengkun. Application value of combined detection of procalcitonin, C-reactive protein, erythrocyte sedimentation rate and white blood cell count in the diagnosis of respiratory tract infection[J]. 中国医药导报, 2020, 17(10): 161-164.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2020/V17/I10/161

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