养阴祛邪法治疗鼻咽癌放疗后口干症的效果

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Abstract Objective To investigate clinical efficacy of nourishing yin and removing pathogenic factors in treating patients with xerostomia after radiotherapy for nasopharyngeal carcinoma. Methods From October 2016 to October 2018, 84 patients with xerostomia after radiotherapy for nasopharyngeal carcinoma were selected from Chongqing University Cancer Hospital. According to the random number table method, they were divided into control group and treatment group, with 42 cases in each group. Total dose of nasopharynx was 68-76 Gy + 10 mL of Kangfuxin Solution, three times a day was in control group. On the basis of control group, treatment group was added with traditional Chinese medicine for nourishing yin and eliminating pathogenic factors. Two groups were treated with one month as a course of treatment, a total of three courses of treatment. The dry mouth score, stimulated salivary flow and parotid flow (PSV, EDV, RI, D) between two groups were observed before and after treatment. Results After treatment, the score of dry mouth degree in two groups was lower than that before treatment, and stimulating saliva flow was more than that before treatment, and the improvement in treatment group was more significant than that in control group (P < 0.05 or P < 0.01). The PSV, EDV and D at the first month after radiotherapy in treatment group were lower than those at the third week after radiotherapy, there were significant differences (P < 0.05). The PSV, EDV and D at the first month after radiotherapy in the treatment group were lower than those of control group, there were significant differences (P < 0.05). Conclusion The method of nourishing yin and removing pathogenic factors can obviously improve the symptoms of xerostomia of nasopharyngeal carcinoma patients after radiotherapy, and has a better protective effect on salivary gland.

Key words： Nourishing yin and removing pathogenic factors Nasopharyngeal carcinoma Radiotherapy Xerostomia

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	CHEN Hong WANG Wei LI Peifu LI Fangfei

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CHEN Hong WANG Wei LI Peifu LI Fangfei. Effect of nourishing yin and removing pathogenic factors in the treatment of xerostomia after radiotherapy of nasopharyngeal carcinoma[J]. 中国医药导报, 2020, 17(10): 130-133.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2020/V17/I10/130

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