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| Study on quality characteristics of specification grade of Radix Peucedani medicinal materials in different producing areas |
| LI Yunyun1 PAN Ya′nan1 GUO Tingting1 ZHANG Hong1 LIU Shoujin1 GAO Guangyin2 |
1.College of Pharmacy, Anhui University of Traditional Chinese Medicine, Anhui Province, Hefei 230000, China;
2.Anhui Guangyintang Traditional Chinese Medicine Corporation Co., Ltd, Anhui Province, Bozhou 236800, China |
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Abstract Objective To explore the differences in quality characteristics between the Radix Peucedani of the ancestral cultivars of different producing areas, and to provide a reference for the establishment of the standards of the classification of Peucedani Radix. Methods In January 2018, 20 batches of graded samples were collected from five production areas including Ningguo Zhongxi, Ningguo Nanshan, Ningguo Yunti, Anhui Chizhou, and Zhejiang Tuoling. A total of 10 individuals were selected to measure the diameter at 1/3 of the head and the total length of Tiaohu. The thin layer chromatography method was used to qualitatively identify the medicinal materials with the reference materials of Praeruptorin A, Praeruptorin B, qianhucoumarin E. The alcohol-soluble extracts were tested according to the requirements of the 2015 edition of the Chinese Pharmacopoeia; and the content of three coumarins was determined by high performance liquid chromatography. Results The data of different grades of medicinal materials from the same place of origin had crossover phenomenon, but the mean values of different grades of medicinal materials from different places of origin had little difference and fluctuated in a small range. The 20 batches of samples all showed the same color spots in the same position as the control. The contents of the extracts of different grades of crude drugs all meet the requirements of the 2015 edition of the Chinese Pharmacopoeia, with certain regularity. There were some differences in the content of coumarin among different grades. Conclusion The quality of medicinal materials from the five producing areas regions is consistent. There is no obvious regularity between the appearance and internal components of different grades of Radix Peucedani in the region, but there are some differences in quality, which can be further studied.
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[1] 国家药典委员会.中华人民共和国药典[S].一部.北京：中国医药科技出版社，2015：265.
[2] 金世元.金世元中药传统鉴别经验[M].北京：中国中医药出版社，2010：94-95.
[3] 熊永兴，陈科力，刘义梅，等.药用植物白花前胡资源调查[J].时珍国医国药，2013，24（11）：2786-2789.
[4] 张贵君.现代中药材商品通鉴[M].北京：中国中医药出版社，2001：775-780.
[5] T/CACM 1021.74—2018.中药材商品规格等级前胡[S].北京：中华中医药学会，2018.
[6] 吴文玲，陈佳佳，刘守金，等.HPLC同时测定前胡中3种香豆素成分的含量[J].中国中药杂志，2009，34（9）：1121-1123.
[7] 俞年军，吴文玲，刘守金，等.前胡根的干物质积累与香豆素类成分含量动态研究[J].中国中药杂志，2013，38（10）：1489-1492.
[8] 李运，邱国玉，李晓春，等.基于主成分分析的前胡类药材HPLC特征图谱研究[J].药物分析杂志，2019，39（7）：1323-1329.
[9] 李颖硕，周秀，李瑞芳，等.基于UPLC-Q-TOF /MS 法分析不同产地前胡药材质量[J].中成药，2019，41（5）：1110-1114.
[10] 梁卫青，浦锦宝，程林，等.野生与人工栽培前胡药材中3种香豆素含量比较研究[J].中药材，2014，37（11）：1966-1968.
[11] 陈灵丽，张玲，彭华胜，等.前胡品质的影响因素及其“辨状论质”考[C].第十九届全国药学史本草学术研讨会暨2017年江苏省药学会药学史专业委员会年会论文集，2017：140-145.
[12] 邱晓霞，张玲，岳婧怡，等.宁前胡中3种香豆素含量影响因素的考察[J].中药材，2016，39（4）：713-716.
[13] 中华人民共和国香港特别行政区卫生署.香港中药材标准2005年版[S].第四册.香港：香港特别行政区政府卫生署中医药事务部，2005：225-234.
[14] 牛倩芸，万燕晴，李震宇，等.不同商品等级黄芪质量评价研究[J].中药材，2015，38（6）：1186-1190.
[15] 王媛媛，彭亮，胡本祥，等.不同商品等级远志药材的质量分析研究[J].中草药，2017，48（18）：3833-3840.
[16] 马鸿雁，许滨，范自全，等.西洋参商品规格等级市场调查及探讨[J].中药材，2017，40（8）：1789-1792.
[17] 张忠廉，宋美芳，郭兰萍，等.钩藤药材商品规格等级标准的调查及初步评估[J].中药材，2018，41（3）：644-647.
[18] 李波，高文远，李霞，等.根及根茎类中药材商品规格等级标准研究探讨[J].中国中医药信息杂志，2018，25（2）：6-10.
[19] 张海珠，沙孟晨，李杨，等.不同商品规格等级人参药材的质量特征比较研究[J].中药材，2018，41（11）：2599-2604.
[20] 康传志，周涛，郭兰萍，等.根及根茎类中药材商品规格及等级标准的划分现状分析[J].贵州农业科学，2014， 42（8）：217-220. |
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