加味葶苈大枣泻肺汤联合尿激酶治疗包裹性结核性胸膜炎的效果

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Abstract Objective To observe the effect of modified Jiawei Tingli Dazao Xiefei Decoction combined with Urokinase in the treatment of wrapped tuberculous pleurisy. Methods A total of 46 patients with encapsulated tuberculous pleurisy in the Department of Infectious Diseases, Xinjiang Shache People′s Hospital, Xinjiang Uygur Autonomous Region from August 2018 to June 2019 were selected. According to the random number table method, they were divided into the treatment group (32 cases) and the control group (23 cases). The control group received chest drainage and Urokinase injection and 2HRZE/7HRE antituberculosis treatment based on a standardized antituberculosis regimen, and on this basis, the treatment group was treated with Jiawei Tingli Dazao Xiefei Decoction. The course of treatment was 1 week, followed by standard anti-tuberculosis treatment. After the course of treatment, the disappearance time of pleural effusion, pleural thickness, B-ultrasonic effusion depth, length of hospital stay and traditional Chinese medicine syndrome score of the two groups were observed. Results After treatment, the effusion disappearance time in the treatment group was shorter than that in the control group, and the difference was statistically significant (P ＜ 0.05); the depth of effusion measured by B-ultrasound in the treatment group was significantly lower than that in the control group, and the difference was highly statistically significant (P ＜ 0.01); The pleural thickness of the treatment group was significantly lower than that of the control group, and the difference was highly statistically significant (P ＜ 0.01); the length of hospital stay in the treatment group was shorterer than that of the control group, and the difference was statistically significant (P ＜ 0.05). The scores of various traditional Chinese medicine symptoms in the two groups were lower after treatment than before treatment, and the scores of fever, cough, sputum and chest pain in the treatment group were lower than those in the control group, with statistically significant differences (all P ＜ 0.05). There was no significant difference in the scores of hemoptysis and shortness of breath between the two groups after treatment (P ＞ 0.05). Patients of the two groups had not obvious bleeding, pain, itching and other adverse reactions. Conclusion Jiawei Tingli Dazao Xiefei Decoction can improve the absorption of pleural effusion, improve the degree of pleural thickening, shorten the length of hospital stay and improve the symptoms of traditional Chinese medicine.

Key words： Jiawei Tingli Dazao Xiefei Decoction Urokinase Encapsulation Tuberculous pleurisy

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	Articles by authors
	XUE Jianhua1
	2 CHENG Yang1
	3 CHEN Jianjie1
	3 MA Kang2 ZHOU Lin2 SHI Yahui2 WU Xiangxiang4

Cite this article:

XUE Jianhua1,2 CHENG Yang1,3 CHEN Jianjie1, et al. Effects of Jiawei Tingli Dazao Xiefei Decoction combined with Urokinase in the treatment of encapsulated tuberculous pleurisy[J]. 中国医药导报, 2020, 17(9): 114-117,122.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2020/V17/I9/114

[1] Kim MC，Kim SM，Lee SO，et al. A diagnostic algorithm for tuberculous pleurisy using the ELISPOT assay on peripheral blood and pleural effusion [J]. Infect Dis （Lond），2016，48（9）：688-694.
[2] 唐书福，刘权贤，张建勇，等.胸腔镜联合胸水Gene-Xpert在结核性胸膜炎中的诊断评价[J].中华医院感染学杂志，2018，28（22）：3434-3437.
[3] 陈效友.结核性胸膜炎诊疗进展[J].临床内科杂志，2015， 32（10）：659-663.
[4] 李虹泽，曹锋，樊毅，等.3种方法联合检测在诊断结核性胸膜炎中的应用价值[J].临床肺科杂志，2018，23（11）：1967-1970.
[5] 吴纪峰，赵磊，王瑜玲，等.内科胸腔镜联合尿激酶治疗结核性胸膜炎多房分隔的研究[J].山西医药杂志，2016，45（20）：2394.
[6] 中华人民共和国卫生部.肺结核门诊诊疗规范（2012年版）[J].中国医学前沿杂志：电子版，2013，5（3）：73-75.
[7] 屈清，黄毅.结核性胸膜炎脏层胸膜增厚的超声表现及临床价值[J].延安大学学报：医学科学版，2017，15（1）：46-48.
[8] 胡旭，尚耀民，邢宝春.补肺活血胶囊联合化疗治疗初治结核性胸膜炎阴虚内热证62例临床观察[J].中医杂志，2019，60（18）：1583-1586．
[9] 马喜迎，甘昭平.血府逐瘀汤联合西医常规疗法治疗结核性胸膜炎胸膜增厚临床研究[J].中国中医药信息杂志，2019，26（3）：20-24.
[10] 吴树才，张玲，张新，等.结核性胸膜炎研究进展[J].临床荟萃，2016，31（10）：1048-1053.
[11] 陈存存，王盛，叶军，等.手术治疗与胸腔内尿激酶溶解纤维素治疗包裹性结核性胸膜炎胸膜纤维板增厚患者的疗效比较[J].疑难病杂志，2015，14（7）：740-742.
[12] 黄毅，薛莲，李维，等.超声在尿激酶注射溶解结核性胸腔积液纤维分隔中的应用价值[J].中华医学超声杂志，2019，16（1）：26-30.
[13] 雷春侠，黄毅，刘元，等.胸腔内注射尿激酶对结核性胸膜炎患者胸水化验结果影响的初步临床分析[J].延安大学学报：医学科学版，2018，16（3）：66-69.
[14] 赵琳.悬饮方+尿激酶治疗结核性包裹性胸腔积液疗效及对炎性因子、腺苷酸脱氢酶、乳酸脱氢酶的影响[J].现代中西医结合杂志，2018，27（6）：605-608.
[15] 夏欣田，张伟，李丽娜，等.胸腔内尿激酶注射治疗结核性胸膜炎的疗效评价[J].临床误诊误治，2019，32（3）：25-31.
[16] 刘枫，杨明娟，杜斌，等.地塞米松联合尿激酶治疗结核性胸膜炎的临床效果分析[J].现代生物医学进展，2017， 17（26）：5138-5140.
[17] 汪春梅，李侠，马迎军.胸腔内置管腔内注射尿激酶治疗包裹性积液的临床疗效分析[J].临床肺科杂志，2014， 19（1）：89-91.
[18] 郭玉琪，张永峰，刘恒.经双腔中心静脉导管引流联合尿激酶注射治疗包裹性胸膜炎50例[J].陕西医学杂志，2013，42（7）：917.
[19] 王周勇，贺美俊，麦天勇.胸腔闭式引流联合尿激酶治疗结核性包裹性胸腔积液的临床疗效[J].实用心脑肺血管病杂志，2014，22（7）：25-27．
[20] 韩莉，桑杨，刘云.超声电导仪靶向透药联合胸腔内注入尿激酶治疗结核性包裹性胸膜炎的效果[J].医学综述，2017，23（3）：591-597
[21] 张伟，肖曼，董洪珍，等.结核性胸膜炎中医证候分布与胸水B超相关性探讨[J].辽宁中医药大学学报，2013， 15（12）：35-36.
[22] 徐金平，陈成德，唐苗苗.加味葶苈大枣泻肺汤联合抗结核药物治疗结核性胸膜炎疗效及对免疫功能的影响[J].世界中西医结合杂志，2018，13（11）：1592-1595.