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Clinical study on detection of inflammatory factors and surgical treatment of obstruction of pelvic ureteral junction |
YAN Bing1 SUN Yihai2 HE Wenjun3 HUANG Hengqian3 |
1.Department of Urology, the Third People′s Hospital of Nanning, Guangxi Zhuang Autonomous Region, Nanning 530003, China;
2.Department of Urology, the Third Affiliated Hospital of Guangxi Medical University, Guangxi Zhuang Autonomous Region, Nanning 530031, China;
3.Department of Urology, the First People′s Hospital of Nanning, Guangxi Zhuang Autonomous Region, Nanning 530022, China |
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Abstract Objective To retrospectively analyze the effects of different surgical methods for treating the ureteropelvic junction obstruction (UPJO) on the detection indexes of various inflammatory factors. Methods From January 2014 to June 2019, a total of 89 patients with unilateral lesions of UPJO in Department of Urology of the First People′s Hospital of Naning were selected. Grouped according to the surgical method, retroperitoneal laparoscopy was used as the experimental group (45 cases), while open surgery was used as the control group (44 cases). Detection indexes of inflammatory factors such as C-reactive protein (CRP), procalcitonin (PCT), and white blood cell count of patients were compared between the two groups. Results There was no significant difference in CRP, PCT, and white blood cell count of patients between the two groups before surgery (P > 0.05). CRP, PCT, and white blood cell counts in the two groups after surgery were higher than those before surgery, while those in the experimental group were lower than those in the control group, and the differences were statistically significant (P < 0.05 or P < 0.01). There was no significant difference in the number of positive urine cultures of patients between the two groups after surgery (P > 0.05). Conclusion UPJO surgical trauma can cause stress inflammatory response, causing increased inflammatory factors. However, the increase of inflammatory factors caused by retroperitoneal laparoscopy is significantly lower than that of open surgery, which has advantages over open surgery. It can provide a certain reference for the selection of clinical surgery plan.
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