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| Application of cervical atypical gland cells in cervical cytology |
| XIONG Lin1 WANG Yan1 HE Fengxia1 WANG Congyang1 ZHANG Dawei2 JIN Ning1 |
1.Department of Pathology, the Second Affiliated Hospital of Nanjing Medical University, Jiangsu Province, Nanjing 210029, China;
2.Department of Otolaryngology Head and Neck Surgery, the Second Affiliated Hospital of Nanjing Medical University, Jiangsu Province, Nanjing 210029, China |
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Abstract Objective To investigate the application of atypical cervical gland cells (AGC) in cervical cytology. Methods From January 2012 to August 2019, a total of 34 patients with AGC were diagnosed by liquid-based thin-layer cell test in the Department of Pathology of the Second Affiliated Hospital of Nanjing Medical University, and the histological results were compared and analyzed. Results There were 7 cases (20.59%) of cervical glandular epithelial dysplasia, 2 cases (5.88%) of cervical adenocarcinoma, 4 cases (11.76%) of endometrial adenocarcinoma, and 9 cases of highly squamous intraepithelial lesions involving glands ( 26.47%), 2 cases (5.88%) of poorly differentiated squamous cell carcinoma, 7 cases (20.59%) of chronic endometrial chronic inflammation, 2 cases (5.88%) of endometrial polyps, and cervical glandular microepithelial type Hyperplasia was 1 case (2.94%). According to the type of lesion, they were divided into glandular epithelial lesion group (13 cases) and squamous epithelial lesion group (11 cases). Compared the age composition of the two groups, the difference was statically significant (P ＜ 0.05). Conclusion In the cervical histological control of AGC, if it is a benign or precancerous lesion, most are cervical dysplasia of the glandular epithelium and a large proportion of highly squamous intraepithelial lesions that need to be identified involve the glands; if it is malignant, most are cervical adenocarcinoma or endometrial adenocarcinoma and poorly differentiated squamous cell carcinoma to be identified. In addition, different types of lesions may related to age, and over 40 years of age are the high incidence age of glandular epithelial lesions.
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