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| Clinical study of Jiawei Yanghe Decoction in the treatment of peripheral arterial disease |
| DAI Dandan1 SUI Wenlin1 LI Meiyu2 |
1.Drug Manufacturing Room, Liaoyang Hospital of Traditional Chinese Medicine, Liaoning Province, Liaoyang 111000, China;
2.Department of Geriatrics, Liaoyang Hospital of Traditional Chinese Medicine, Liaoning Province, Liaoyang 111000, China |
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Abstract Objective To investigate the clinical effect of Jiawei Yanghe Decoction treating peripheral arterial disease(PAD). Methods A total of 133 PAD patients in Liaoyang Hospital of Traditional Chinese Medicine were selected from March 2017 to March 2019 and they were divided into the study group (67 cases, conventional western medicine combined with Jiawei Yanghe Decoction) and the control group (66 cases, conventional western medicine) according to the random number table method. The clinical efficacy, adverse reactions, traditional Chinese medition syndrome score, hemorheology indexes and ankle brachial index (ABI), blood flow of dorsalis pedis artery and intermittent claudication distance of patients in the two groups were compared. Results After treatment the total clinical effective rate of the study group was higher than that of the control group (P ＜ 0.05). After 1 month of treatment, the traditional Chinese medition syndrome scores and high blood viscosity, plasma viscosity, hematocrit, red cell assembling index in the two groups were all lower than before treatment, and the study group was lower than the control group (P ＜ 0.05). After 1 month of treatment, the ABI, blood flow of dorsalis pedis artery, intermittent claudication distance were increased in the two groups, and the study group was higher than the control group (P ＜ 0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P ＞ 0.05). Conclusion Jiawei Yanghe Decoction can rapidly improve the clinical symptoms of patients with PAD, with definite curative effect, and also can improve the blood circulation of the body, with good drug safety.
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