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| Study on the status and influencing factors of cognitive function in patients with lung cancer undergoing chemotherapy |
| ZHOU Li1 LIU Yanping2 YAN Wenjing1 DING Rulei1 PENG Lingying1 ZHENG Ya1 ZENG Guqing1▲ NI Xiaoyan1 |
1.School of Nursing, University of South China, Hu′nan Province, Hengyang 421001, China;
2.Department of Infectious Diseases, the First Affiliated Hospital of University of South China, Hu′nan Province, Hengyang 421001, China |
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Abstract Objective To investigate the cognitive function and the influencing factors in patients with lung cancer undergoing chemotherapy, in order to provide reference for the development of reasonable and effective interventions. Methods This study was adopted to “cluster sampling method”. From November 1, 2018 to April 30, 2019, three hurdred cases with lung cancer undergoing chemotherapy in 4 grade of 3A (Class Three/Grade A) hospital in Hengyang were collected. The general information questionnaire and the mini-mental state examination (MMSE) were used. The cognitive ability and cognitive level of lung cancer patients undergoing chemotherapy were analyzed, and the influencing factors were analyzed. Results The average MMSE scores of lung cancer patients undergoing chemotherapy were (25.530±3.283) scores, and 41 (14.4%) patients were low cognitive level. The results of univariate analysis showed that age, marital status, education level, occupation, medical payment form, physical exercise, understanding of the disease, TNM stage, chemotherapy cycle and metastasis had an impact on the cognitive function of lung cancer patients undergoing chemotherapy (P < 0.05). Multivariate linear stepwise regression analysis showed that age, marital status, education level, physical exercise , Karnofsky score and chemotherapy cycle were the main influencing factors of cognitive function in patients with lung cancer undergoing chemotherapy (P < 0.05). Conclusion There are some patients with low cognitive level and their cognitive function is affected by many factors. It will be beneficial for medical staff to understand those patients cognitive function through cognitive evaluation, and do good to formulate effective interventions to help those patients to improve their cognitive function.
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