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| Discussion of the surgical methods of 13 young patients with locally advanced cervical squamous cell carcinoma |
| KANG Haili1 ZHAO Qun1 WU Yumei1 RUAN Xiangyan2 DUAN Wei1 |
1.Department of Gynecologic Oncology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100006, China;
2.Department of Endocrinology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100006, China |
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Abstract Objective To explore the surgical stage of young patients with locally advanced cervical cancer while preserving reproductive endocrine function. Methods From May 2016 to March 2018, 13 cases of locally advanced cervical cancer patients ＜ 40 years old admitted to Beijing Obstetrics and Gynecology Hospital, Capital Medical University were selected. Laparoscopic surgical staging and ovarian cryopreservation were performed before radiotherapy. Case data were reviewed to evaluate the accuracy of CT/MRI in judging lymph node metastasis and the feasibility of preserving reproductive endocrine function. Results The sensitivity of lymph metastasis in patients with locally advanced cervical cancer was 66.7% by CT/MRI and Specificity was 70.0%. Thirteen patients underwent ovarian cryopreservation, and two underwent ovarian transplantation after treatment, with stable hormone levels and complete remission of menopausal symptoms. Conclusion CT/MRI is not sensitive and specific enough to evaluate lymph node metastasis. Laparoscopic pelvic and para-aortic lymph node resection for locally advanced cervical cancer is an important means to evaluate lymph node metastasis. Ovarian cryopreservation can be a new option to save and restore reproductive endocrine function in young cervical cancer patients.
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