2型糖尿病患者颈围与良性前列腺增生的相关性研究

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Abstract Objective To investigate the correlation between neck circumference (NC) and benign prostatic hyperplasia (BPH) in patients with type 2 diabetes mellitus (T2DM). Methods From September 2015 to June 2017, 216 cases with T2DM in Jizhong Energy Fengfeng Group Hospital were recruited. According to whether BPH was combined or not, they were divided into N-BPH group (n = 118) and BPH group (n = 98). According to the NC measurement levels, they were divided into Q1 subgroup: 33.4 cm≤NC≤35.7 cm (n=53), Q2 subgroup: 35.7 cm＜NC≤39.1 cm (n = 56), Q3 subgroup: 39.1 cm＜NC≤39.9 cm (n = 51), Q4 subgroup: 39.9 cm＜NC≤43.9 cm (n = 56). The general and clinical data of all subjects were collected, and the NC levels were measured. All subjects underwent B-ultrasound examination of prostate, and the international prostate symptom score (IPSS) was performed for all subjects. Logistic regression analysis was used for correlation analysis. Results NC, body mass index (BMI), waist circumference, waist-hip ratio, systolic blood pressure (SBP), diastolic blood pressure (DBP) and the levels of glycosylated hemoglobin, fasting plasma glucose (FPG), high density lipoprotein cholesterd (HDL-C)， total cholesterol and triglyceride in BPH group were significantly higher than those in N-BPH group, with statistically significant differences (all P < 0.05). The prostate volume (PV) of Q2, Q3 and Q4 subgroups was higher than that of Q1 subgroup, the postvoid residual (PVR) and IPSS scores of Q3 and Q4 subgroups were higher than those of Q1 subgroup, the PV of Q3 and Q4 subgroups was higher than that of Q2 subgroup, and the IPSS scores of Q4 subgroup were higher than those of Q2 and Q3 subgroups, with statistically significant differences (all P < 0.05). Logistic regression analysis showed that NC, BMI, SBP and FPG were risk factors for BPH. Conclusion NC is significantly increased in T2DM patients with BPH. NC may become an influencing factor for T2DM patients with BPH, which has clinical significance.

Key words： Neck circumference Benign prostatic hyperplasia Type 2 diabetes mellitus Insulin resistance

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	SHANG Shuxia1 WEI Junfeng2▲ ZHAO Junkui3 DUAN Lijun1 NIU Yun1 SUN Qiujie4 ZHOU Hao5

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SHANG Shuxia1 WEI Junfeng2▲ ZHAO Junkui3 DUAN Lijun1 NIU Yun1 SUN Qiujie4 ZHOU Hao5. Correlation research of neck circumference and benign prostatic hyperplasia in type 2 diabetic mellitus patients[J]. 中国医药导报, 2020, 17(6): 77-80.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2020/V17/I6/77

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