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Advances in the application of rs-fMRI in the study of migraine in traditional Chinese medicine |
ZHANG Jiwei1 WU Hongyun2▲ |
1.College of Acupuncture and Massage, Shandong University of Traditional Chinese Medicine, Shandong Province, Ji′nan 250014, China;
2.the 3th Encephalopathy Department, the Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Shandong Province, Ji′nan 250014, China |
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Abstract Migraine is a common primary headache, characterized by moderate and severe throbbing headache, which seriously affects patients′ quality of life and brings heavy economic burden to social medical system. Resting-state functional magnetic resonance (rs-fMRI) is a fMRI technology based on the blood-oxygen level dependent mechanism, which can reflect the living brain function without any trauma, especially suitable for the objective study of traditional Chinese medicine. This paper reviewes the research on rs-fMRI in pathogenesis, syndrome and treatment of traditional Chinese medicine migraine in recent years, and build up a theoritic basis for the application of rs-fMRI as an objective biomarker in the exploration of pathogenesis of migraine, in order to explore the syndrome diagnosis, differential diagnosis, therapeutic mechanism and other studies in traditional Chinese medicine.
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