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Advancesin research on the relationship between human papilloma-virus infection and genital lesions |
ZHANG Shihua SUN Hui DU Yandan▲ |
Department of Laboratory, Inner Mongolia Forestry General Hospital the Second Clinical Medicine College of Inner Mongolia University for Nationalities, Inner Mongolia Autonomous Region, Yakeshi 022150, China |
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Abstract Human papillomavirus (HPV) can be divided into high-risk type and low-risk type according to pathogenicity. The high-risk type mainly causes cervical cancer in women and the penis cancer in men, while the low-risk type mainly causes genital warts. Different genotypes cause certain differences in disease types. HPV-16 is the main type of female squamous cell carcinoma; HPV-18 is the main type of female adenocarcinoma and adenosquamous carcinoma; HPV-16 and HPV-18 infection are the main types of male penile cancer; the main types of female genital warts and male genital warts and infertility are HPV-6 and HPV-11. Currently, there are two preventive and therapeutic vaccines for HPV on the market. Different populations should choose vaccines in a targeted and reasonable manner, which is essential for preventing and eliminating HPV.
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