柳州地区0～16岁未成年人维生素D水平研究及其与季节变化的关系

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Abstract Objective To investigate the levels of 25-hydroxy vitamin D [25-(OH) D] in minors of 0-16 years old in Liuzhou area, and provide scientific reference for reasonable supplement of vitamin D (Vit D). Methods A total of 3441 minors aged 0 to 16 who underwent a health check-up at the Children′s Health Department of Liuzhou Maternal and Child Health Hospital from January to December 2017 were selected. The study subjects were divided into four groups according to age, including 161 children in the group of 0 to 1 year old, 1716 children in the group of 1 to 3 years old, 1184 children in the group of 3 to 6 years old, and 380 children of the > 6 years old group; according to season 1209 minors were divided in the winter and spring group, 2232 in the summer and autumn group. The levels of 25-(OH) D were detected by electrochemical luminescence method, and the relationship between 25-(OH) D and age, sex, and season were analyzed. Results There was no statistically significant difference in the levels of 25-(OH) D among different minors aged 0 to 16 in Liuzhou area (P ＞ 0.05). Among them, the constituent ratios of adequate, insufficient, and lacking Vit D were 77.4%, 19.5% and 3.1% respectively. Comparison of 25-(OH) D levels in each age groups, the differences were highly statistically significant (P ＜ 0.01). The differences of percentage of Vit D deficiency and insufficiency in each age group was highly statistically significant (P ＜ 0.01). The difference of proportion of Vit D deficiency, insufficiency, and adequacy of different genders in the ＞6 years old group was highly statistically significant (P ＜ 0.01). The proportion of deficiency and insufficiency Vit D in the winter and spring group was significantly higher than that in the summer and autumn group, and the difference was highly statistically significant (P ＜ 0.01). Conclusion The reasonable supplement of Vit D should be paid more attention, especially the schoolchildren, adolescents, girls and the supplement of Vit D in winter and spring.

Key words： Liuzhou area Minors 25- hydroxy vitamin D Season

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	WEI Xiaoni DING Yanling FU Jinjian

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WEI Xiaoni DING Yanling FU Jinjian. Vitamin D nutritional status and the relationship with climatic changes research of minors aged 0-16 in Liuzhou area[J]. 中国医药导报, 2020, 17(3): 49-52.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2020/V17/I3/49

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