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| Application value of dynamic contrast-enhanced MRI combined with diffusion-weighted magnetic resonance imaging in staging diagnosis of cervical cancer |
| OYANG Qin1 XU Hai2 MA Zhen3 |
1.Department of Radiology, Huangjiahu Hospital, Hubei University of Chinese Medicine, Hubei Province, Wuhan 430065, China;
2.Department of Gynecology, Huangjiahu Hospital, Hubei University of Chinese Medicine, Hubei Province, Wuhan 430065, China;
3.Department of Internal Medicine, Huangjiahu Hospital, Hubei University of Chinese Medicine, Hubei Province, Wuhai 430065, China |
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Abstract Objective To explore the application effect of DCE-MRI combined with DWI (DCE-MRI+DWI) in staging diagnosis of cervical cancer and to guide clinical diagnosis. Methods From December 2017 to December 2018, 83 patients with cervical cancer confirmed by pathological examination in Huangjiahu Hospital, Hubei University of Chinese Medicine were selected. All patients underwent routine MRI and dynamic contrast-enhanced MRI combined with DWI before operation, the accuracy of the two methods of inspection were explored. Results There were significant differences in Ktrans and kep values of DCE-MRI and ADC value of DWI in patients with different FIGO clinical stages and differentiated degrees of cervical cancer （P < 0.05）. The accuracy of diagnosis of cervical cancer pathological staging with conventional MRI and DCE-MRI+DWI was 62.65% and 95.18%, respectively, and the difference was statistically significant （P < 0.05）. In the analysis of tissue invasion of adjacent tissues, the sensitivity and specificity of conventional MRI were 83.33% and 78.72%, respectively. The sensitivity and specificity of DCE-MRI+DWI were 97.22% and 95.74%, respectively. The sensitivity and specificity of DCE-MRI+DWI were higher than the conventional MRI, and the differences were statistically significant (P < 0.05). Conclusion Compared with conventional MRI, DCE-MRI+DWI is more accurate in the diagnosis of cervical cancer staging, which is worthy of clinical application.
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