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Application progress of triple antibiotic paste in the treatment of periodontal disease and endodontic disease |
LYU Haodong1 HUANG Min2 |
1.Stomatological College and Hospital, Anhui Medical University, Anhui Province, Hefei 230031, China;
2.Department of Stomatology, Zhongnan Hospital of Wuhan University, Hubei Province, Wuhan 430071, China |
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Abstract The oral microecotogical environment is anfractuous, and a variety of pathogenic bacteria will lead to infection of root canal, periodontitis, and periapical periodontitis. The occurrence of these diseases are related to the structure of teeth and periodontal tissues because they will induced different kinds of pathogenic bacteria to accumulate in the corresponding parts. In order to effectively deal with this kind of disease, the application of antibiotic combination is particularly important. As a combination of three kinds of antibiotics, such as Ciprofloxacin, Metronidazole and Minocycline, triple antibiotic paste (TAP) has a good antibacterial effect, which has been used to control the infection in root canals and to promote pulp revascularization. This article mainly reviews and summarizes the application of TAP in the treatment of periodontal disease and endodontic disease.
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