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| Nutritional status and ECOG score in patients after hematopoietic stem cell transplantation |
| REN Guangxu1 LI Minghua2 YU Changrong2 LIAN Jiawei1 WANG Jing2 ZHANG Jianping2 |
1.Institute of Food and Nutrition Development, Ministry of Agriculture, Beijing 100081, China;
2.Bone Marrow Transplantation Unit, Hebei Yanda Lu Daopei Hospital, Hebei Province, Sanhe 065201, China |
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Abstract Objective To analyze the nutritional status and eastern cooperative oncology group (ECOG) scores of patients underwent hematopoietic stem cell transplantation. Methods From June 2012 to March 2017, 95 patients with hematopoietic stem cell transplantation in Hebei Yanda Lu Daopei Hospital were selected as research objects. ECOG scale was used to evaluate the patients′performance status. The weight of the patients was recorded before and after operation of hematopoietic stem cell transplantation. Nutritional status of patients were analyze on the bases of ECOG scores and weight changes. The platelet (PLT), red blood cell (RBC), hemoglobin, total protein and albumin of peripheral blood were compared before and after transplantation. Results ①After operation of hematopoietic stem cell transplantation, 82.11% of patients lost weight, while 17.89% gained weight. ②After transplantation, 71.58% of the patients in ECOG score were concentrated at 2-3 levels, 2.10% of patients had no change in physical status and 4.21% of the patients had totally lost the living ability. ③After transplantation, RBC and PLT in the patients were lower than those of before transplantation, with statistically significant differences (P ＜ 0.05). Conclusion Hematopoietic stem cell transplantation can significantly affect the nutritional status of patients and subsequently affect the life quality. Therefore, the preoperative of nutritional status should be valued in patients who underwent hematopoietic stem cell transplantation and appropriate nutritional interventions should be taken.
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