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Experience of Professor Xuan Guowei in the treatment of children Henoch-Schonlein purpura nephritis |
LU Jiping LI Hongyi DANG Ruonan XIONG Shuqing SI Weizhen WU Yuansheng |
The Second Clinical Medical College, Guangzhou University of Chinese Medicine, Guangdong Province, Guangzhou 510405, China |
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Abstract Henoch-Schonlein purpura nephritis is the most common secondary nephropathy in children. It is lingering and difficult to cure. According to the characteristics of children′s constitution, Professor Xuan Guowei considers that this disease is mainly caused by insufficient natural endowment, and accumulation of heat toxin is the superficial cause. He put forward treatment ideas that “reinforcing the vital essence and strengthening the primordial qi, and solving disorders of blood system”. Combining characteristics of Lingnan region, the treatment mainly consists of nourishing yin and tonifying the kidney, combined with the Chinese herbs of clearing heat and cooling blood, activating blood and stop bleeding, removing toxin and stasis. Thus, he inventing Xueguanyan Decoction and pay attention to protect children′s spleen and stomach by using light and mild herbs to invigorating vital qi without stagnation and purgation without damage vital qi and get satisfied curative effects by judging and weighing deficiency and excess and differential diagnosis of stage of disease in clinical.
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[1] Jelusic M,Sestan M,Cimaz R,et al. Different histological classifications for Henoch-Schonlein purpura nephritis:which one should be used? [J]. Pediatr Rheumatol Online J,2019,17(1):10.
[2] Karadag SG,Tanatar A,Sonmez HE,et al. The clinical spectrum of Henoch-Schonlein purpura in children:a single-center study [J]. Clin Rheumatol,2019,38(6):1707-1714.
[3] Nie S,He W,Huang T,et al. The spectrum of biopsy-proven glomerular diseases among children in china:a national,cross-sectional survey [J]. Clin J Am Soc Nephrol,2018, 13(7):1047-1054.
[4] 赵辨.中国临床皮肤病学[M].南京:江苏科学技术出版社,2010:872-873.
[5] Huang X,Wu X,Le W,et al. Renal prognosis and related risk factors for henoch-schonlein purpura nephritis:a chinese adult patient cohort [J]. Sci Rep,2018,8(1):5585.
[6] 李兰,应旭旻.儿童过敏性紫癜肾炎常用药物治疗进展[J].中国乡村医药,2018,25(7):69-70,72.
[7] 罗笑容,许尤佳.中西医结合儿科学[M].北京:科学出版社,2008:141-145.
[8] 禤国维.平调阴阳,治病之宗[J].新中医,2002,34(2):3-4.
[9] 陈达灿,李红毅,欧阳卫权.国医大师禤国维[M].北京:中国医药科技出版社,2016:141-142.
[10] 刘卓勋,杨京华,黄振祺.岭南地区小儿体质辨证分型初探[J].新中医,2014,46(5):236-238.
[11] 苏宝印,李立伟.糖皮质激素治疗肾脏病所致副作用得中医药对策[J].中国中西医结合肾病杂志,2010,11(11):1015-1016.
[12] 洪阁,戴永红,刘培勋,等.仙鹤草化学成分和药理作用研究进展[J].药学服务与研究,2008,8(5):362-364.
[13] 赵其光.本草求原[M].北京:中国中医药出版社,2016.
[14] 张小琼,侯晓军,杨敏,等.乌梅的药理作用研究进展[J].中国药房,2016,27(25):3567-3570.
[15] 陶欣艺,周勖,任宇红.抗过敏中草药活性成分的药效评价[J].江西师范大学学报:自然科学版,2012,36(6):554-557.
[16] 邓士贤,施越华.紫草的药理研究[J].云南医药,1983,4(4):232-237.
[17] 丘和明,邱健行,刘国普,等.紫珠草静脉注射液治疗上消化道出血临床疗效得初步观察[J].中国中医急症,1993, 2(4):152.
[18] 任永欣,沈映君.紫苏叶的现代药理及应用研究进展[J].四川生理科学杂志,2002,24(2):51-53.
[19] 裴悦,平瑞月,杨贤平,等.国医大师禤国维运用过敏煎治疗荨麻疹经验[J].四川中医,2019,37(4):7-8.
[20] 杨晓曦.中药芡实对糖尿病肾病大鼠蛋白尿的降低作用及其化学成分研究[D].南宁:广西医科大学,2015.
[21] 李玲,孙元章,李刚.灵芝生物活性成分及其药理作用研究进展[J].南方农业,2019,13(4):50-55.
[22] 赵丽萍,常克.基于数据挖掘的常克教授治疗紫癜性肾炎用药规律研究[J].世界中医药,2017,12(8):1759-1763.
[23] 朱丽.大剂量维生素E加超微量肝素对过敏性紫癜患儿氧化应激及微炎症状态的影响[J].河北医学,2018, 24(3):378-382.
[24] 徐海玲.小剂量肝素预防小儿紫癜性肾炎的临床研究[J].中国医药科学,2018,8(10):48-50.
[25] 蒋凤艳,常克.引火归元法治疗小儿紫癜性肾炎血尿(肝肾阴虚证)的疗效研究[J].世界中医药,2017,12(8):1739-1742.
[26] 庄加原.儿童过敏性紫癜性肾炎治疗进展[J].医学理论与实践,2016,29(11):1437-1439. |
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