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| The relationship between retinal ganglion cell complex thickness and retinal nerve fiber layer thickness and its effect on neovascular glaucoma |
| XIONG Yunfan LI Qin |
| Department of Ophthalmology， the First Affiliated Hospital of Kunming Medical University，Yunnan Province, Kunming 650000, China |
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Abstract Objective To research the relationship between the thickness of retinal ganglion cell complex (mGCC) and retinal nerve fiber layer (pRNFL) and its effect on neovascular glaucoma. Methods From May 2016 to May 2019, 40 cases with NVG patients receiving fourier domain optical coherence tomography (FD-OCT) examination in the First Affiliated Hospital of Kunming Medical University were selected as NVG group. In the same period, 40 cases with normal persons receiving FD-OCT examination were selected as normal group. The mGCC thickness and pRNFL thickness were compared between two groups. Pearson accumulates correlation analysis was used to analyze the correlation between the mGCC thickness and pRNFL thickness. And the diagnostic effectiveness for NVG was evaluated. Results The thickness of GCC-average, GCC-superior, GCC-inferior and the thickness of RNFL-average, RNFL-temporal, RNFL-superior, RNFL-nasal, RNFL-inferior in NVG group were lower than those in normal group, and the differences were statistically significant (all P < 0.05). Pearson accumulates correlation analysis showed that mGCC thickness at all sites were positively correlated with pRNFL thickness. mGCC thickness and pRNFL thickness at all sites have diagnostic effect on NVG (P < 0.01). Conclusion In the diagnosis of NVG, mGCC thickness can be used as an important supplementary measure of pRNFL thickness, which is worthy of application and promotion.
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