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Clinical effect of endoscopic retrograde cholangiopancreatography combined with endoscopic sphincterotomy of papilla in treatment of biliary tract disease |
ZHOU Lan WANG Jianxiang PENG Dongshu |
Department of Gastroenterology, Chengdu Fifth People′s Hospital, Sichuan Procince, Chengdu 611130, China |
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Abstract Objective To investigate the clinical effects of endoscopic retrograde cholangiopa ncreatography (ERCP) combined with endoscopic sphincterotomy (EST) in the treatment of biliary tract disease. Methods The clinical data of 124 patients with biliary tract disease admitted to the Fifth People′s Hospital of Chengdu from January 2017 to December 2018 were retrospectively analyzed. According to different treatment plans, they were divided into control group and observation group, with 62 cases in each group. The control group was treated with conventional calculus removed of laparotomy, and the observation group was treated with ERCP combined with EST. The clinical efficacy, clinical indicators, index levels of inflammatory factor, and complications were compared between the two groups. Results The total effective rate of the observation group was significantly higher than that of the control group (P < 0.05). In the observation group, abdominal pain relief, intestinal ventilation, serum amylase return to normal, and hospitalization time were significantly shorter than the control group (P < 0.05). Before treatment, there was no statistically significant difference between the two groups in tumor necrosis factor-α and cardiopulmonary resuscitation (P > 0.05). After treatment, the levels of inflammatory factors were decreased in the two groups, and the observation group was lower than the control group (P < 0.05), the incidence of total complications in the observation group was higher than that in the control group (P < 0.05). Conclusion For patients with biliary system diseases required surgery, the ERCP+EST program for surgical treatment has the advantages of rapid recovery and small trauma, which is worthy of clinical application.
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[1] 程刚,田平,王照红,等.早期治疗性ERCP治疗急性胆源性胰腺炎的疗效分析[J].中国现代医生,2017,55(22):24-26.
[2] 赵昌杰,陈林.经内镜乳头括约肌小切开联合柱状球囊扩张术治疗胆总管结石36例分析[J].中国临床研究,2016,29(1):81-83.
[3] 张亚飞,潘伟康,武阿丽,等.内镜下逆行胰胆管造影术中置入胰管支架预防术后胰腺炎效果观察[J].临床误诊误治,2017,65(11):77-79.
[4] 张杰,杨传春,杨斌.乳头括约肌小切开联合气囊扩张治疗胆总管结石25例疗效观察[J].医学临床研究,2018, 35(3):580-582.
[5] Lyu Y,Cheng Y,Wang B,et al. What is impact of nonsteroidal anti-inflammatory drugs in the prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis:a meta-analysis of randomized controlled trials [J]. Bmc Gastroenterol,2018,18(1):106-108.
[6] 赵光.经内镜逆行性胰胆管造影术治疗急性胆源性胰腺炎疗效观察[J].淮海医药,2017,35(5):554-556.
[7] 王继恒,何玉琦,高革.多次行经内镜逆行胰胆管造影患者的临床特点分析[J].临床肝胆病杂志,2015,31(10):1645-1647.
[8] 张亚飞,潘伟康,吴兵,等.ERCP引导下腔内射频消融联合支架置入治疗恶性胆管肿瘤合并梗阻的临床疗效及短期预后分析[J].解放军医药杂志,2017,29(9):48-51.
[9] 闫国强.经内镜逆行性胰胆管造影术在胰胆疾病诊治中的临床应用[J].航空航天医学杂志,2018,29,183(4):459-460.
[10] 高峰,依尔潘·艾山.ERCP合并EST对胆道疾病疗效及其并发症的临床分析[J].临床消化病杂志,2016,28(2):76-78.
[11] 段卫星.内镜逆行胰胆管造影术下十二指肠乳头括约肌切开取石术联合腹腔镜下硬性胆道镜保胆治疗胆囊合并胆总管结石疗效分析[J].中国医学工程,2016(6):116-117.
[12] 阮巍山,岑川,林宏凯,等.内镜下乳头括约肌小切开联合大球囊扩张术治疗难治性胆总管结石101例临床分析[J].中国医药科学,2017,7(7):210-213.
[13] 刘爱志,林桂仁,宁丽娜.经内镜治疗胆总管结石的观察与护理[J].职业卫生与病伤,2006,21(3):206.
[14] 贺永锋,汤善宏,郭文伟,等.内镜下乳头括约肌小切开联合大球囊扩张治疗老年胆总管多发巨大结石的效果及安全性分析[J].临床肝胆病杂志,2018,34(2):158-161.
[15] Zhang ZF,Duan ZJ,Wang LX,et al. Aggressive Hydration With Lactated Ringer Solution in Prevention of Postendoscopic Retrograde Cholangiopancreatography Pancreatitis:A Meta-analysis of Randomized Controlled Trials [J]. J Clin Gastroenterol,2017,51(3):17-21.
[16] 邹好楠,邹密密,肖海燕,等.超声造影对甲状腺乳头状癌被膜侵犯患者的诊断价值[J].西部医学,2019,31(1):124-128.
[17] 王峰.内镜黏膜下剥离术在早期大肠癌及癌前病变的临床研究[J].成都医学院学报,2017,12(1):73-76,80.
[18] 吴小伟.利胆排石汤联合内镜下逆行胰胆管造影及乳头括约肌切开术治疗胆总管结石的临床分析[J].医学理论与实践,2019,32(4):67-69.
[19] 黎亮,赵凤庆,周俊,等.ERCP和PTCD治疗结石性梗阻性黄疸的对比研究[J].中国现代医生,2017,55(9):78-81.
[20] 谷化剑,郭宇廷,韩民,等.经内镜逆行胰胆管造影术与腹腔镜胆道手术在肝内外胆管结石治疗中的疗效评价[J].中国内镜杂志,2017,23(8):32-37.
[21] 汤厚阔,全竹富.ERCP联合LC治疗胆囊结石合并胆总管结石的临床分析[J].肝胆外科杂志,2016,24(4):273-275.
[22] 姜维,高竹清,王拥军.经内镜逆行胰胆管造影术后穿孔诊断及治疗研究进展[J].中华消化内镜杂志,2018, 35(6):449-451.
[23] 左旭辉,肖湘,饶会波,等.无痛内镜下逆行胰胆管造影术在限定时间内选择性胆胰管插管的临床应用[J].中国医药导报,2018,15(35):130-133.
[24] 姚利,陈先祥,涂华华,等.内镜逆行性胰胆管造影术与腹腔镜胆总管探查术治疗胆囊切除术后胆总管结石的疗效比较[J].临床外科杂志,2018,26(2):121-123. |
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