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| Clinical effect of Xiaoshuan Enteric-Coated Capsules in the treatment of convalescent stage of cerebral infarction of qi deficiency and blood stasis syndrome |
| WANG Yun LI Yingyi TANG Lingtao ZHAO Xuemeng |
| Department of Neurology, the Xingtai Third Hospital, Hebei Province, Xingtai 054000, China |
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Abstract Obiective To explore the clinical effect of Xiaoshuan Enteric-Coated Capsules in the treatment of convalescent stage of cerebral infarction of qi deficiency and blood stasis syndrome. Methods Using convenient sampling method, 120 patients of convalescent stage of cerebral infarction of qi deficiency and blood stasis syndrome admitted to the Xingtai Third Hospital of Hebei Province from June 2018 to June 2019 were selected and they were divided into the control group and the observation group according to the random number table method, with 60 cases in each group. The control group was treated with rehabilitation treatment and preventive treatment. The observation group was given Xiaoshuan Enteric-Coated Capsules on the basis of the control group. The therapeutic effect and the incidence of adverse reactions were observed in the two groups, the scores of motor function and daily living ability before and after treatment were compared between the two groups. The serum homocysteine and serum neurotrophic index before and after treatment were measured in the two groups. Results The total effective rate of the observation group was significantly higher than that of the control group, the difference was statistically significant (P ＞ 0.05). Compared with before treatment, the scores of motor function and daily life ability of the two groups increased significantly，and the observation group was higher than the control group, the differences were statistically significant (P ＜ 0.05). Compared with before treatment, the level of serum homocysteine in the two groups decreased, and the observation group was lower than the control group, the differences were statistically significant (P ＜ 0.05). Compared with before treatment, the levels of brain-derived neurotrophic factor and vascular endothelial growth factor in the two groups increased significantly, the observation group was higher than the control group, and the differences were statistically significant (P ＜ 0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P ＞ 0.05). Conclusion Xiaoshuan Enteric-Coated Capsules has a good clinical effect in the treatment of convalescent stage of cerebral infarction of cerebral infarction of qi deficiency and blood stasis syndrome, which can improve the treatment effect, improve the symptoms, without significantly increasing adverse reactions, which is worthy of clinical promotion and application.
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