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| Application of artificial intelligence in drug discovery |
| SUN Yajing LI Chunyang ZENG Xiaoxi |
| West China Biomedical Big Data Center, West China Hospital, Sichuan University, Sichuan Province, Chengdu 610041, China |
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Abstract Artificial intelligence plays an important role in drug discovery field. This paper summarizes artificial intelligence technology applications in the medical field, such as to efficiently screen therapeutic targets and design drugs, saving the costs of drug discovery and shortening the time required for drug discovery; to deal with the problems of molecular characteristics, water-solubility, toxicity and oral absorption potential in preclinical development stage; to analyze issues about drug redirection, patient recruitment, clinical trial design optimization in the drug clinical research stage; as well as to analyze the research information and to make a drug safety evaluation after drug approval and marketing. This paper studies the achievements and problems of artificial intelligence research in the key stages of drug discovery, preclinical development, clinical research and approval for marketing, and looks forward to the trend of new drug research and development driven by artificial intelligence technology. The purpose is to provide reference for relevant scientific research and technical personnel engaged in the landing of artificial intelligence in the field of medicine.
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