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Influence of comprehensive psychological intervention on depressive mood, life health quality and neurotransmitter in patients with recurrent depression |
TANG Wenjuan1 QIAN Yiping2▲ GU Kangying3 CHEN Xuefei4 |
1.Department of Psychology, the Third People′s Hospital of Huai′an City, Jiangsu Province, Huai′an 223001, China;
2.Department of Nursing, the Third People′s Hospital of Huai′an City, Jiangsu Province, Huai′an 223001, China;
3.Preventive Care Center, the Third People′s Hospital of Huai′an City, Jiangsu Province, Huai′an 223001, China;
4.Clinical Laboratory, the Third People′s Hospital of Huai'an City, Jiangsu Province, Huai'an 223001, China |
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Abstract Objective To study the influence of comprehensive psychological intervention on depressive mood, life health quality and neurotransmitter in patients with recurrent depression. Methods From April 2014 to June 2015, 80 patients with recurrent depression in the Third People's Hospital of Huai'an City were divided into control group (40 cases) and observation group (40 cases) by random number table. Patients in the control group were treated with routine clinical intervention, while those in observation group were treated with comprehensive psychological intervention combined with routine clinical intervention. The scores of depressive and life quality and the serum content of monoamine neurotransmitter in the two groups were compared. Results Before the intervention, there were no significant differences in the scores of depressive and life quality and the serum content of monoamine neurotransmitter between the two groups (P > 0.05). After intervention, the scores of depressive in the observation group were lower than those in the control group, the scores of life quality in the observation group were higher than those in control group, the levels of NE, 5-HT, DA in the observation group were higher than those in control group (P < 0.05). Conclusion Comprehensive psychological intervention can relieve depression and improve the quality of life in patients with recurrent depression.
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