ICU昏迷患者口腔感染易感因素分析及干预对策

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Abstract Objective To explore the susceptible factors and intervention measures of oral infection in coma patients in intensive care unit (ICU). Methods From January 2017 to January 2019, 117 ICU coma patients admitted to Beijing Tiantan Hospital, Capital Medical University were selected to observe their oral infection. Data were collected including gender, age, education, body mass index, oral health status, oral mucosal injury, antibiotic use, and systemic diseases including hypertension and diabetes. Chi-square test or Fisher′s exact probability method were used to analyze the factors related to oral infection in ICU patients with coma, and multivariate Logistic regression was used to analyze the risk factors of oral infection. Results Among the 117 patients, 24 had oral infection, with an infection rate of 20.51%. No oral infection occurred in 93 cases, accounting for 79.49%. There were statistically significant differences between the two groups in complicated with diabetes mellitus or not, oral health status, oral mucosal injury, and antibiotics use or not (all P ＜ 0.05). Multivariate Logistic regression analysis showed that patients complicated with diabetes mellitus (OR = 1.648, 95%CI: 1.271-2.381, P ＜ 0.05), poor oral hygiene (OR = 2.367, 95%CI: 1.628-3.319, P ＜ 0.05), accompanied by oral mucosal injury (OR = 2.981, 95%CI: 1.892-3.946, P ＜ 0.05), and absence of antibiotics (OR = 1.983, 95%CI: 1.462-2.763, P ＜ 0.05) were risk factors affecting oral infection in ICU patients with coma. Conclusion ICU patients with coma have a high rate of oral infection, which is affected by many factors. Complications of diabetes, poor oral hygiene, accompanied by oral mucosa injury, and absence of antibiotics are the susceptible factors for oral infection. In order to reduce oral infection, relevant oral care evaluation and intervention should be taken according to the susceptible factors.

Key words： Intensive care unit Oral infection Susceptible factors Oral care

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	HUANG Lei1 YUAN Yuan2 WU Ruiqing1▲

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HUANG Lei1 YUAN Yuan2 WU Ruiqing1▲. Analysis of susceptible factors of oral infection in ICU patients with coma and intervention measures[J]. 中国医药导报, 2019, 16(32): 103-106.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2019/V16/I32/103

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