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Quantitative analysis of benign and malignant thyroid nodules under contrast-enhanced ultrasound |
CHEN Jie1 ZHENG Li1 WANG Meiyu1 ZHOU Dawei1 DU Jing2 JIANG Xinhui1 XIN Jun1 |
1.Department of Ultrasound,Shanghai Baoshan District Hospital of Traditional Chinese and Western Medicine, Shanghai 201999, China;
2.Department of Ultrasound, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China |
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Abstract Objective To explore the quantitative analysis of benign and malignant thyroid nodules under contrast-enhanced ultrasound. Methods From October 2016 to December 2018, 60 patients with a total of 62 thyroid nodules who proposed to be operated on Shanghai Baoshan District Hospital of Traditional Chinese and Western Medicine were selected, and all patients obtained definite pathological results. All patients were treated with contrast-enhanced ultrasound examination and time-intensity curve (TIC) parameters in thyroid nodules and surrounding normal tissues were quantitatively analysed. The difference of peak intensity (ΔPI), the difference of Slope (ΔSlope) and the difference of area under the curve (ΔAUC) were recorded. The ROC curve were drew to evaluate the value of differential diagnosis of benign and malignant thyroid nodules. Results When the cut-off values of ΔPI, ΔSlope and ΔAUC in differential diagnosis of benign and malignant thyroid nodules were -3.25, -1.27, -89.65, the sensitivity were 83%, 75%, 75% and the specificity were 72%, 57%, 77%, respectively. Conclusion Quantitative analysis of TIC curve parameters in contrast-enhanced ultrasound may be helpful in differential diagnosis of benign and malignant thyroid nodules.
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