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Medicinal chemistry teaching innovation and practice for the cultivation of drug discovery talents |
ZHANG Yongqiang LI Hao LI Jian MAO Fei DENG Weiping MA Hongmei |
School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China |
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Abstract The fast-growing pharmaceutical industry of China calls for the cultivation of many qualified drug discovery talents urgently. The research of medicinal chemistry is the major driving force of drug discovery. Therefore, the corresponding course teaching represents main approach for the cultivation of drug discovery talents. Herein, three strategies against the problems in present college medicinal chemistry course teaching were demonstrated, including topic-based teaching extension, comprehensive teaching methods innovation and two-dimensional teaching evaluation. These strategies were initially proved efficient in motivating the students to learn more practical drug design skills and in developing the innovative thinking ability for drug discovery. Furthermore, the initial teaching practice outcome was evaluated and some constructive suggestions were thus presented accordingly.
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[1] 王茜,陆叶营,严庞科,等.中国新药研发模式转变的探讨[J].药学进展,2013,37(10):488-492.
[2] 朱迅.中国新药创制升级在即[J].药学进展,2016,40(11):833-834.
[3] 张广洲,王凤山.对我国新药研发现状的几点思考[J].齐鲁药事,2007,26(1):37-38.
[4] 陈晓洁,王玮.我国新药研发和发展的现状[J].海峡药学,2009,21(1):159-161.
[5] 丁凤琴.我国新药研发动力不足现状分析[J].海峡药学,2012,24(12):289-291.
[6] 曹桂彬,邹学慧,姚慧.我国医药企业战略实施中存在的问题及对策研究[J].科技创新导报,2010,7(9):229.
[7] 赵金朋,冯国忠.我国医药产业研发现状与瓶颈分析[J].现代商贸工业,2012,24(8):25-26.
[8] 杜文婷,邓卫平,唐赟.大药学背景下的药物化学创新教育[J].药学教育,2009,25(5):23-25.
[9] 梁颖,霍强,吴成柱,等.药物化学教学与创新型人才培养的探讨[J].基础医学教育,2015,17(12):1051-1053.
[10] 李红霞,刘瑞江,杨永青,等.基于创新型人才培养的药物化学教学研究[J].山东化工,2015,3(44):133-134.
[11] 季红,张建业,张超.基于复合型创新人才培养的《药物化学》教学改革探讨[J].广东化工,2016,19(43):191-192.
[12] 刘志国,代彦丽.浅析PBL教学法与传统教学法在药物化学教学中的效果[J].广州化工,2013,41(23):151-152.
[13] 张江华,郭伟,宋爽.PBL法在药物化学教学中的应用[J].辽宁中医药大学学报,2012,14(7):185-186.
[14] 邹登峰,黄金萍,吕好平,等.PBL教学模式在天然药物化学教学中的运用[J].教育教学论坛,2015,7(29):140-141.
[15] 冯学珍,裴世成,蒙华琳,等.LBL+PBL双轨教学法在天然药物化学教学中的应用[J].广州化工,2015,43(18):151-152.
[16] 孙晶波,姜爽,崔龙.PBL与传统教学相结合的教学模式在药物化学教学中的应用[J].求医问药,2013,11(7):342-343.
[17] 敖桂珍,温红.PBL结合TBL教学法在药物化学课程中的探索[J].基础医学教育,2015,17(9):773-775.
[18] 蓝海,王燕.PBL教学法在药学专业无机化学教学中的探索[J].大理学院学报,2013,12(6):81-83.
[19] 曹洪玉,冯宝民,牟红梅.以药物结构为核心的药物化学教学设计[J].广州化工,2014,42(17):204-206.
[20] 霍强,葛敏梁,梁颖,等.浅谈药物结构在药物化学教学中的核心地位[J].科技创新导报,2009,6(5):150.
[21] 林友文,陈莉敏,陈艳.药物化学知识结构的组织位[J].药学教育,2007,23(6):34-36. |
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