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| Analysis on the related factors of post-operative cognitive dysfunction in elderly patients undergoing cardiac surgery under cardiopulmonary bypass |
| YUE Qin WU Xiaochen WANG Jian DING Sheng XIN Mei ZHANG Jinbao |
| Department of Cardiovascular Surgery, Western Military General Hospital, Sichuan Province, Chengdu 610083, China |
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Abstract Objective To explore the related factors of postoperative cognitive dysfunction (POCD) in elderly patients undergoing cardiac surgery under cardiopulmonary bypass (CPB). Methods Two hundred and six patients undergoing cardiac valve surgery under CPB in the Cardiac Surgery Department of Western Military General Hospital from March 2017 to March 2019 were enrolled. The patients were divided into POCD group (58 cases) and non-POCD group (148 cases), according to whether they had POCD or not, while the related factors of POCD were analyzed. Results Patients in the POCD group were older than that in the non-POCD group, while the education years, CPB time, aortic occlusion time, postoperative mechanical ventilation time, postoperative ICU hospitalization time of patients in POCD group were significantly longer than those in non-POCD group, and the differences were statistically significant (P ＜ 0.05). The related factors of the incidence of POCD in elderly patients undergoing cardiac surgery under CPB were age, the education years, CPB time and aortic occlusion time (P ＜ 0.05). Conclusion The occurrence of POCD in elderly patients undergoing cardiac surgery under CPB is related to the age, education years, CPB time and aortic occlusion time. Clinical doctors should pay a high degree of attention and take targeted preventive measures to reduce the risk of POCD.
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