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| Clinical effect of Bushen Zhuanggu Decoction in the treatment of diabetic ostecporosis |
| FU Jiangtao HONG Bin ZHANG Jianlin▲ LEI Liang ZHANG Ning |
| The Third Department of Bone Traumatology, Baoji Hospital of Traditional Chinese Medicine, Shaanxi Province, Baoji 721001, China |
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Abstract Objective To observe the clinical effect of Bushen Zhuanggu Decoction in the treatment of diabetic ostecporosis. Methods Eighty-two cases of patients with diabetic ostecporosis treated in Baoji Hospital of Traditional Chinese Medicine from October 2015 to January 2017 were selected as research objects, and they were divided into observation group and control group by random number table method, with 41 cases in each group. Both groups were given conventional basic therapy, on basis of conventional basic therapy, the control group was given Calcium Supplement with Vitamin D Chewable Tablets and Elcatonin Injection. On basis of control group, the observation group was added with Bushen Zhuanggu Decoction. Both groups were taken 4 weeks as a course, after 3 courses of treatment, the clinical effects were observed, the blood glucose, glycosylated hemoglobin, bone mineral density and serum calcium, phosphorus of the two groups before and after treatment were detected, the adverse reactions were recorded. Results The total effective rate of observation group was 95.1%, which was higher than that of control group (82.9%), the difference was statistically significant (P ＜ 0.05). After treatment, the levels of fasting blood glucose, 2 h postprandial blood glucose, glycosylated hemoglobin of the two groups were significantly lower than those before treatment, the differences were highly statistically sighificant (P ＜ 0.01), and the indices above in the observation group after treatment were all lower than those of control group (P ＜ 0.05). After treatment, the spinal bone mineral density of the two groups were all higher than those before treatment, the spinal bone mineral density of observation group was higher than that of control group, the differences were all statistically significant (P ＜ 0.05), the levels of serum calcium in the two groups were higher than those before treatment, and the levels of serum phosphorus were lower than those before treatment, but the differences were not statistically significant (P ＞ 0.05), and the differences between the two groups after treatment were also not statistically significant (P ＞ 0.05). During treatment, there were no obvious adverse reactions in the two groups. Conclusion On basis of western medicine, Bushen Zhuanggu Decoction can significantly improve the clinical symptoms of patients with diabetic ostecporosis, increase bone mineral density, control blood glucose, which is worthy of clinical promotion and application.
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