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| Progress in the role of autophagy in the pathogenesis of rheumatoid arthritis |
| QIN Qian1 QING Yufeng2 ZHOU Wenjun2 WANG Dan2 XIONG Qin3 YANG Xiaohong1，4 |
1.Department of Microbiology and Immunology, College of Basic Medical Sciences, North Sichuan Medical College, Sichuan Province, Nanchong 637000, China; 2.Department of Rheumatology and Immunology, Affiliated Hospital of North Sichuan Medical College, Sichuan Province, Nanchong 637000, China;
3.Department of Geriatrics, Affiliated Hospital of North Sichuan Medical College, Sichuan Province, Nanchong 637000, China;
4.Party Committee Office, the Second Affiliated Hospital of North Sichuan Medical College, Sichuan Province, Nanchong 637000, China |
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Abstract Rheumatoid arthritis is a chronic, inflammatory autoimmune disease, its pathogenesis is not yet fully clear. Autophagy widely exists in eukaryotes. It is a metabolic process that maintains normal physiological activity and homeostasis in cells. Its abnormalities are related to the occurrence and development of many diseases. In recent years, autophagy has attracted wide attention and become one of the research hotspots. Autophagy can affect the occurrence and development of rheumatoid arthritis in many ways. This article reviews this aspect.
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