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Research progress on correlation between CD4+ new subsets of Th9 cells and common autoimmune diseases |
ZHANG Huining1 WANG Jiajun2 |
1.Department of Nurse, An-Ning Sub-Hospital in 940th Hospital in Joint Logistic Support Force of the People′s Liberation Army of China, Gansu Province, Lanzhou 730070, China;
2.Teaching and Research Section of Medical Immunology, School of Medicine, Hubei Minzu University, Hubei Province, Enshi 445000, China |
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Abstract Th9 cells are a newly discovered subset of differentiated CD4+T cells that participate in the body′s immune response by secreting interleukin-9 (IL-9). In patients with autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus, the proportion of Th9 cells and the content of IL-9 in the blood and tissues will change greatly, indicating that it is closely related to the occurrence and development of autoimmune diseases. This paper reviews the research progress on the correlation between Th9 cells and common autoimmune diseases in recent years.
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