糖尿病合并持续植物状态胰岛素注射患者低血糖的发生情况

Abstract
Figure/Table
References (20)
Related Citation (15)

Download: PDF (442 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To investigate occurrence and causes of hypoglycemia in insulin-injecting diabetic patients with persistent vegetative state. Methods A total of 40 patients with diabetes mellitus complicated with persistent vegetative state insulin intradermal injection to control blood sugar were selected from February 2017 to March 2018 in Three Departments of Cadre Ward, the Seventh Medical Center in PLA General Hospital. Blood sugar was monitored. According to occurrence of hypoglycemia, the patients were divided into hypoglycemia group (18 cases) and non-hypoglycemia group (22 cases). According to the frequency of hypoglycemia, hypoglycemia patients were divided into multiple-occurrence group (8 cases) and low-occurrence group (10 cases). The incidence and causes of hypoglycemia were counted. Gender, age, course of diabetes, systolic blood pressure, diastolic blood pressure, glycosylated hemoglobin, triglyceride and low density lipoprotein cholesterol were compared among groups. Results There were 18 cases of hypoglycemia (45.00%), 83 times of hypoglycemia, 49 times of postprandial hypoglycemia (59.04%) and 34 times of night hypoglycemia (40.96%). The main cause of postprandial hypoglycemia was nasal feeding reflux. The main causes of night hypoglycemia were hypoglycemia before bed and insulin dosage forms. The course of diabetes mellitus in low-occurrence group was shorter than that in multiple-occurrence group, and the level of glycosylated hemoglobin was higher than that in multiple-occurrence group (P < 0.05). Conclusion Insulin-injecting diabetic patients with persistent vegetative state are more likely to suffer from hypoglycemia with longer course of disease and stricter blood sugar control. Clinical attention should be paid to nasal feeding reflux and insulin dosage form.

Key words： Diabetes mellitus Persistent vegetative state Hypoglycemia Insulin injection

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	LI Guoying1 CHENG Qianpeng2 ZHANG Hui1 LI Huili1

Cite this article:

LI Guoying1 CHENG Qianpeng2 ZHANG Hui1 LI Huili1. Occurrence of hypoglycemia in insulin-injecting diabetic patients with persistent vegetative state[J]. 中国医药导报, 2019, 16(27): 69-72.

URL:

http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2019/V16/I27/69

[1] 中华医学会糖尿病学分会.中国2型糖尿病防治指南（2017年版）[J].中国糖尿病杂志，2018，10（1）：4-67.
[2] 《中华医学会急诊医学学会意识障碍研究专业组》.持续性植物状态的命名、定义及诊断标准[J].现代临床医学生物工程杂志，1996，2（3）：232.
[3] Feinkohl I，Aung PP，Keller M，et al. Severe hypoglycemia and cognitive decline in older people with type 2 diabetes：the Edinburgh type 2 diabetes study [J]. Diabetes Care，2014，37（2）：507-515.
[4] Association AD. Foundations of care and comprehensive medical evaluation [J]. Diabetes Care，2016，39（Suppl 1）：s23-s35.
[5] 赵茜，蒋利丹.医院到家庭连续护理干预对持续植物状态出院患者的效果[J].护理学杂志，2015，30（2）：7-10.
[6] 张俊清.糖尿病患者低血糖的危害及预防[J].药品评价，2010，28（7）：18-20.
[7] Desouza C，Salazar H，Cheong B，et al. Association of hypoglycemia and cardiac ischemia A study based on continuous monitoring [J]. Diabetes Care，2018，26（5）：1485-1489.
[8] Seaquist ER，Miller ME，Bonds DE，et al. The impact of frequent and unrecognized hypoglycemia on mortality in the ACCORD study [J]. Diabetes Care，2017，35（2）：409-414.
[9] 钱荣立.高度警惕老年糖尿病患者夜间无症状低血糖引发致命性心律失常的危险[J].中国糖尿病杂志，2016，24（3）：198-199.
[10] Cha SA，Yun JS，Lim TS，et al. Severe hypoglycemia and ardiovascular or all-cause mortality in patients with type 2 diabetes [J]. Diabetes Metab J，2016，40（3）：202-210.
[11] Pi?諭tkiewicz P，Buraczewska-Leszczyńska B，Kuczerowski R，et al. severe hypoglycemia in elderly Patients with type 2 diabetes and coexistence of cardiovascular history [J]. Kardiol Pol，2016，74（8）：779-785.
[12] Tsujimoto T，Yamamoto-Honda R，Kajio H，et al. Vital signs，QT prolongation，and newly diagnosed cardiovascular disease during severe hypoglycemia in type 1 and type 2 diabetic patients [J]. Diabetes Care，2013，37（1）：217-225.
[13] Reno CM，Daphna-Iken D，Chen YS，et al. Severe hypoglycemia-induced lethal cardiac arrhythmias are mediated by sympathoadrenal activation [J]. Diabetes，2013，62（10）：3570-3581.
[14] Gill GV，Woodward A，Casson IF，et al. Cardiac arrhythmia and nocturnal hypoglycaemia in type 1 diabetes—the "dead in bed" syndrome revisited [J]. Diabetologia，2016， 52（1）：42-45.
[15] 曹月琴，鲁亚玲.老年2型糖尿病并发低血糖的原因分析及预防[J].中国热带医学，2009，9（7）：1250-1251.
[16] 廖淑金，黄萍，傅明捷，等.老年2型糖尿病患者低血糖特征的临床研究[J].中国糖尿病杂志，2016，24（3）：205-209.
[17] Fukuda M，Doi K，Sugawara M，et al. Survey of hypoglycemia in elderly people with type 2 diabetes mellitus in Japan [J]. J Clin Med Res，2015，7（12）：967-978.
[18] Schutt M，Fach EM，Seufert J，et al. Multiple complications and frequent severe hypoglycaemia in "elderly" and "old" patients with type 1 diabetes [J]. Diabet Med，2018， 29（8）：e176-e179.
[19] Brian M，Simon R. Hypoglycaemia in clinical diabetes [M]. Third Edition. John Wiley & Sons Ltd.，2014：265-283.
[20] Yong YM，Shin KM，Lee KM，et al. Intensive individualized reinforcement education is important for the prevention of hypoglycemia in patients with type 2 diabetes [J]. Diabetes Metab J，2015，39（2）：154-163.