|
|
|
| Influencing factors of blood donation volunteers to join the Chinese Marrow Donor Program |
| LI Mo1 LIN Minshi1 HE Minjing1 LIANG Shaogang1 LIU Jiajun2 ZHANG Ling2 |
1.Shunde Blood Central of Foshan City, Guangdong Province, Foshan 528300, China;
2.Department of Hematology, the Third Affiliated Hospital, Sun Yatsen University, Guangdong Province, Guangzhou 510630, China |
|
|
|
Abstract Objective To investigate the influencing factors of donation of hematopoietic stem cells by voluntary blood donors and their awareness of donation of hematopoietic stem cells, establish the information bank of hematopoietic stem cells donors in Shunde Area of Guangdong Province. Methods The self-designed questionnaires on voluntary blood and hematopoietic stem cell donation were used to anonymously investigate on 1200 volunteer blood donors from March 1st to September 30th, 2018 in Shunde Blood Central of Foshan City, Guangdong Province ("our blood central" for short). And the information data from 685 volunteers who entered the database of our blood central from 2006 when Chinese Marrow Donor Program (CMDP) was established to September 30, 2018, were collected and analyzed. Results A total of 924 questionnaires were included in the study, results showed majority of volunteers were male (54.0%), staff (29.5%) and students (28.8%), most of them had junior degree (39.2%), high school degree or below (35.5%). And young people aged 18-35 years accounted for 74.9%; 685 CMDP volunteers were mainly male (71.1%) and workers (30.1%). Most education level was high school and below (50.5%) and young people aged 18-35 years (65.3%) was more than than other aged. Compared with voluntary blood donors, there were highly statistically significant differences in gender, educational background, occupation and age distribution among CMDP volunteers (P < 0.01). There also were highly statistically significant difference in the number of blood donations between CMDP volunteers and voluntary blood donors (P < 0.01). Conclusion CMDP volunteers are all voluntary blood donors, encouraging voluntary blood donors to join the CMDP should focus on male, middle-aged, low-educated and worker volunteers. The more times people donate blood, the more chances they have to learn about hematopoietic stem cells and the more likely they are to join CMDP. Strengthening volunteers′ understanding of the cause of blood donation and hematopoietic stem cells and protecting their rights and interests are beneficial to the development of blood donation and hematopoietic stem cell donation in Foshan.
|
|
|
|
|
|
[1] Bensinger W. Peripheral blood stem cell transplantation [J]. Cancer Treat Res，1995，76：169-193.
[2] Amouzegar A，Dey BR，Spitzer TR. Peripheral Blood or Bone Marrow Stem Cells? Practical Considerations in Hematopoietic Stem Cell Transplantation [J]. Transfus Med Rev，2019，33（1）：43-50.
[3] 《中国组织工程研究与临床康复》杂志社学术部.造血干细胞移植的临床应用：现状与概况及未来[J].中国组织工程研究与临床康复，2010，14（1）：140-141.
[4] 王健民，温宏升.造血干细胞移植在恶性血液病治疗中的应用[J].上海第二医科大学学报，2004，24（5）：325-330.
[5] 王丹丹，武文杰，李茜，等.脐血造血干细胞移植的研究进展[J].医学综述，2014，20（8）：1377-1379.
[6] 肖芷芳，李勇华，庞妍，等.53例非亲缘外周血造血干细胞捐献者健康调查[J].中华全科医学，2012，10（2）：270-271.
[7] 陈晓霞，王智明，罗贤生，等.造血干细胞动员和采集对正常供者的影响[J].中国组织工程研究与临床康复，2010， 14（23）：4281-4284.
[8] Bosi A，Bartolozzi B. Safety of bone marrow stem cell donation：a review [J]. Transplant Proc，2010，42（6）：2192-2194.
[9] Halter J，Kodera Y，Ispizua AU，et al. Severe events in donors after allogeneic hematopoietic stem cell donation [J]. Haematologica，2009，94（1）：94-101.
[10] Anderlini P，Chan FA，Champlin RE，et al. Long-term follow-up of normal peripheral blood progenitor cell donors treated with filgrastim： no evidence of increased risk of leukemia development [J]. Bone Marrow Transplant，2002，30（10）：661-663.
[11] Li Q，Wang K，Guo W，et al. Cytomegalovirus pneumonia in a patient with T-lymphoblastic leukemia/lymphoma after allogeneic hematopoietic stem cell transplantation：A case report [J]. Medicine （Baltimore），2019，98（4）：e14221.
[12] 郭翔，惠飞，张博，等.非亲缘造血干细胞捐献者的心理焦虑原因分析与应对[J].中国输血杂志，2015，28（9）：1165-1167.
[13] 丁娜妮，焦阳，高晟，等.温州市居民非亲缘外周血造血干细胞捐献意愿的影响因素[J].温州医科大学学报，2018， 48（1）：72-75.
[14] 苏力，闫超，郑磊，等.影响造血干细胞志愿捐献者捐献决定的心理因素初步研究[J].中国心理卫生杂志，2016， 30（11）：806-811.
[15] Switzer GE，Dew MA，Butterworth VA，et al. Understanding donors′ motivations：a study of unrelated bone marrow donors [J]. Soc Sci Med，1997，45（1）：137-147.
[16] Khomenko VI，Bychkov VV，Bazyka DA. State of development of hematopoietic stem cell transplantation in the europe and world [J]. Lik Sprava，2014，（7-8）：117-121.
[17] 冯刚丽.浅谈如何减少造血干细胞捐献者的流失[J].长江大学学报：自科版，2013，10（15）：60-61.
[18] 马敬东，金新政，罗青，等.造血干细胞捐献登记国际比较研究[J].卫生软科学，2003（3）：40-45.
[19] 金新政，邹庆波.造血干细胞捐献者招募机制的影响因素与分析[J].卫生软科学，2003（3）：15-18.
[20] 耿兴敏.中华骨髓库面临双重困境[N].中国妇女报，2005-7-11（08）.
[21] 张颖，徐雅靖，曾辉，等.造血干细胞移植后生存质量调查[J].临床血液学杂志，2012，25（5）：562-565.
[22] 李鹏，徐辉.《2017年意大利共识指南:血液系统恶性肿瘤以及接受造血干细胞移植患者HBV再激活的筛查、监测、预防和预防性治疗的建议》摘译[J].临床肝胆病杂志，2017，33（11）：2087-2090. |
|
|
|
