膝骨关节炎实验动物模型现状研究进展

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Abstract According to National Standard for Laboratory Animals, knee osteoarthritis models are divided into small animal models, large and medium animal models and primate animal models. The commonly used animal models at home and abroad are classified according to spontaneous model and induced model. Spontaneous model includes natural spontaneous model and genetically modified model, while inductive model includes diet induction model, drug injection induction model, operation induction model, braking induction model and cold induction model. The selection of different models and the application of modeling methods are suitable for different research purposes.

Key words： Knee osteoarthritis Animal models Induced model methods Research progress

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	Articles by authors
	YU Pei1
	2 LIU Lu1 LI Zhijuan1
	2 FU Yuanbo1 YUAN Fang1 LI Bin1▲

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YU Pei1,2 LIU Lu1 LI Zhijuan1,2 FU Yuanbo1 YUAN Fang1 LI Bin1▲. Research progress of experimental animal models of knee osteoarthritis[J]. 中国医药导报, 2019, 16(27): 41-44.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2019/V16/I27/41

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