|
|
Spatial-temporal distribution of syphilis and its influencing factors in China (excluding Hong Kong, Macao and Taiwan) from 2010 to 2016 |
ZHANG Huilin1 CHEN Yuyan2 XIAO Yao3 LI Shulian4▲ |
1.Department of Clinical Laboratory, Zhongshan Hospital Affiliated to Xiamen University, Fujian Province, Xiamen 361004, China;
2.Department of Clinical Laboratory, the Fifth Hospital of Xiamen City, Fujian Province, Xiamen 361101, China;
3.Department of Science and Education, Xiamen Traditional Chinese Medicine Hospital, Fujian Province, Xiamen 361009, China;
4.President′s Office, Maternity and Child Care Hospital of Huli District in Xiamen City, Fujian Province, Xiamen 361006, China |
|
|
Abstract Objective To explore spatial-temporal distribution characteristics of syphilis epidemic situation in China (excluding Hong Kong, Macao and Taiwan) from 2010 to 2016 and its social influencing factors. Methods Spatial aggregation of syphilis epidemic situation in China (excluding Hong Kong, Macao and Taiwan) from 2010 to 2016 was analyzed by using geographic information software ArcGIS and spatial data analysis software GeoDa. Spatial data processing software SaTScan was used to retrospectively analyze syphilis epidemic situation from 2010 to 2016. Stata was used to carry out panel data regression analysis of syphilis epidemic situation. Results Global spatial autocorrelation analysis showed that there was no spatial aggregation of syphilis incidence in China (excluding Hong Kong, Macao and Taiwan) from 2011 to 2015 (Moran′s I = 0.0444 to 0.1099, P > 0.05), however, in 2010 (Moran′s I = 0.2524, P < 0.05) and 2016 (Moran′s I = 0.1932, P < 0.05), syphilis incidence in China (excluding Hong Kong, Macao and Taiwan) was spatially aggregated. The results of local autocorrelation analysis showed that Jiangsu, Shanghai and Fujian were in the high-high region in 2010, Gansu was in the low-high region in 2013-2016, and all regions in China (excluding Hong Kong, Macao and Taiwan) were not in the high-high region in 2011-2012. Retrospective spatio-temporal scanning analysis revealed that there was one primary clustering region (Shanghai, Zhejiang, RR = 2.49) and six secondary clustering regions (Guangxi, Xinjiang, Chongqing, Liaoning, Inner Mongolia and Ningxia, RR = 1.44-3.50). The results of panel data regression analysis showed that per capita GDP and consumption level were the influencing factors of the incidence of syphilis (P < 0.05). Conclusion The epidemic situation of syphilis has obvious characteristics of spatial-temporal aggregation and is affected by social demographic factors. Discussing the characteristics of spatial-temporal aggregation of syphilis can provide a positive reference for syphilis control strategy and evaluation of the effect of prevention and control measures.
|
|
|
|
|
[1] Liu LL,Lin Y,Zhuang JC,et al. Analysis of serum metabolite profiles in syphilis patients by untargeted metabolomics [J]. J Eur Acad Dermato,2019,33:1378-1385.
[2] 陶长余,章士军,陈郁.2005-2014年我国梅毒发病率趋势分析及预测[J].职业与健康,2015,31(21):3026-3027.
[3] Zhu B,ZhuY,Liu JL,et al. Notifiable sexually transmitted infections in china:epidemiologic trends and spatial changing patterns [J]. Sustainability,2017,9(10):1784.
[4] Cao WT,Li R,Ying JY,et al. Spatiotemporal distribution and determinants of gonorrhea infections in mainland China:a panel data analysis [J]. Public Health,2018,162:82-90.
[5] Xiao G,Xu C,Wang J,et al. Spatial-temporal pattern and risk factor analysis of bacillary dysentery in the Beijing-Tianjin-Tangshan urban region of China [J]. BMC Public Health,2014,14(1):998.
[6] Health N,Commission FP. Report on China′s migrant population development [D]. China Population Publishing House,2017.
[7] 关鹏,曹爽,黄德生,等.2005-2011年中国大陆地区梅毒疫情时空分布[J].中国感染控制杂志,2014,13(5):257-262.
[8] 严华美,杨瑛,张星灿,等.上海市闵行区2005-2016年梅毒疫情分析[J].复旦学报,2017,44(5):585-589.
[9] 徐晓燕.常熟市2005-2015年梅毒疫情分析[J].江苏预防医学,2017,28(3):300-301.
[10] Wong NZ,Chen L,Joseph D,et al. Distribution of reported syphilis cases in South China:spatiotemporal analysis [J]. Sci Rep,2018,8(1):9090.
[11] 王培安,罗卫华,白永平.基于空间自相关和时空扫描统计量的聚集比较分析[J].人文地理,2012,27(2):119-127.
[12] Goujon-Bellec S,Demoury C,Guyot-Goubin A,et al. Detection of clusters of a rare disease over a large territory performance of cluster detection methods [J]. Int J Health Geogr,2011,10:53.
[13] 廖一兰,王劲峰,杨维中,等.传染病多维度聚集性探测方法[J].地理学报,2012,67(4):435-443.
[14] 杨振,王念,王宇.中国性病疫情的时空差异与经济驱动机制——以淋病、梅毒为例[J].热带地理,2016,36(5):761-766.
[15] Chang BA,Pearson WS,Owusu-Edusei K. Correlates of county-level nonviral sexually transmitted infection hot spots in the US:application of hot spot analysis and spatial logistic regression [J]. Ann Epidemiol,2017,27(4):231-237.
[16] Tan NX,Messina JP,Yang LG,et al. A spatial analysis of county-level variation in syphilis and gonorrhea in Guangdong Province,China [J]. PLoS One,2011,6:e19648.
[17] Chen X,Peeling RW,Yin Y,et al. The epidemic of sexually transmitted infections in China:implications for control and future perspectives [J]. BMC Med,2011,9:111.
[18] Chen W,Zhou F,Hall BJ,et al. Spatial distribution and cluster analysis of risky sexual behaviors and STDs reported by Chinese adults in Guangzhou,China:a representative population-based study [J]. Sex Transm Infect,2016,92(4):316-322.
[19] 唐小静,曾庆,赵寒,等.重庆市2008-2012年手足口病空间聚集性及影响因素研究[J].中国人兽共患病学报,2014,30(12):1196-1200.
[20] Fu R,Zhao JK,Wu Dan,et al. A spatiotemporal meta-analysis of HIV/syphilis epidemic among men who have sex with men living in mainland China [J]. BMC Infect Dis,2018,18(1):652. |
|
|
|