经支气管镜针吸活检联合快速现场评价诊断纵隔病变18例及文献复习

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Abstract Objective To evaluate the diagnostic value of transbronchial needle aspiration (TBNA) combined with rapid on-site evaluation (ROSE) technique in mediastinal lesions. Methods Eighteen patients with mediastinal lesions from June 2016 to June 2018 in the First People′s Hospital of Lianyungang were selected, all the patients were given the detection of TBNA and ROSE technique. The diagnostic efficiency of TBNA combined with ROSE, and diagnose accordance rate with final pathological examination were calculated, the occurrence of complications of TBNA combined with ROSE technique were observed. Results The sensitivity of TBNA combined with ROSE technique in the diagnosis of mediastinal lesions was 70.6%, the specificity was 100.0%, positive predictive value was 100.0%, negative predictive value was 16.7%, miss rate was 29.4%, and no misdiagnosis patient. The diagnose accordance rate of BNA combined with ROSE technique and final pathological examination was 72.2%, the complications included 2 cases of sinus tachycardia, 5 cases of mild hemorrhage, and 1 case of hoarseness, no massive hemorrhage. Conclusion TBNA combined with ROSE technique has high diagnostic efficiency in diagnosing mediastinal lesions, which could significantly reduce repeated TBNA.

Key words： Transbronchial needle aspiration Rapid on-site evaluation Mediastinum Lymph node Lung cancer

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	ZHAO Qing1* WU Xingping2* LIANG Chengcheng2 ZHANG Chenying2 SHI Jiaxin2 LI Jiashu2

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ZHAO Qing1* WU Xingping2* LIANG Chengcheng2 ZHANG Chenying2 SHI Jiaxin2 LI Jiashu2. The transbronchial needle aspiration combined with rapid on-site evaluation in diagnosis of 18 cases with mediastinal lesions and literature review[J]. 中国医药导报, 2019, 16(25): 153-157.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2019/V16/I25/153

[1] 马芸，杨会珍，张苑，等.经支气管针吸活检术的过去、现在和未来[J].中华结核和呼吸杂志，2014，37(11）：862-864.
[2] Ozturk A，Gullu YT. Excellence in non-small cell lung cancer staging by endobronchial-TBNA：Comparison with PET-CT and surgery [J]. MITAT，2019,28（4）.
[3] 欧振宇，周爱莲.现场细胞学评估在介入肺病学中的应用现况[J].临床肺科杂志，2015，20（10）：1886-1889.
[4] Dai X，Niu B，Yang XQ，et al. Combined transbronchoscopic needle aspiration （TBNA） and rapid on-site cytological evaluation （ROSE） for diagnosis of tuberculous mediastinal lymphadenitis：A case report [J]. Medicine，2018，97（37）：e11724.
[5] 谭慧，晋萍，张磊，等.现场快速评估在纤维支气管镜活检中的应用研究[J]，云南医药，2018，39（2）：97-100.
[6] 张磊，叶联华，陈颖，等.现场快速评估在经超声支气管镜针吸活检中的应用评价[J]，中国当代医药，2017，24（24）：7-10.
[7] 王孟昭，陈勇，钟巍，等.经支气管镜淋巴结针吸活检对肺癌的诊断意义[J].中华肿瘤杂志，2006，28（7）：533-535.
[8] 李世荣，杨刚，陆志伟，等.经支气管镜检查联合针吸活检术在肺癌诊断中的临床应用价值[J].皖南医学院学报，2016，35（05）：451-452.
[9] Arslan Z，Ilgazli A，Bakir M，et al. Conventional vs. endobronchial ultrasound-guided transbronchial needle aspiration in the diagnosis of mediastinal lymphadenopathies [J]. Tuberk Toraks，2011，59（2）：153-157.
[10] 荣福，萧淑华，刘静，等.常规经支气管镜针吸活检与超声引导下经支气管镜针吸活检对纵隔病变诊断的比较[J].中华结核和呼吸杂志，2011，34（2）：120-122.
[11] 王栋，尚斌，姜淑娟.经支气管镜超声引导针吸活检术在常规经支气管镜针吸活检术检查阴性的纵隔疾病中的应用价值[J].中华结核和呼吸杂志，2014，37（4）：279-282.
[12] Nardecchia E，Cattoni M，Dominioni L. Endobronchial ultrasound-transbronchial needle aspiration for mediastinal staging of non-small cell lung cancer： variability of results and perspectives [J]. J Thorac Dis，2017，9（Suppl 5）：S418-S424.
[13] Sung S，Crapanzano JP，DiBardino D，et al. Molecular testing on endobronchial ultrasound （EBUS） fine needle aspirates （FNA）：Impact of triage [J]. Diagn Cytopathol，201８，46（2）：122-130.
[14] Collins BT，Chen AC，Wang JF，et al. Improved laboratory resource utilization and patient care with the use of rapid on-site evaluation for endobronchial ultrasound fine-needle aspiration biopsy [J]. Cancer Cytopathol，2013，121（10）：544-551.
[15] Baram D，Garcia RB，Richman PS. Impact of Rapid On-Site Cytologic Evaluation During Transbronchial Needle Aspiration [J]. Chest，2005，128（2）：869-875.
[16] Sehgal IS，Dhooria S，Aggarwal AN，et al. Impact of Rapid On-Site Cytological Evaluation （ROSE） on the Diagnostic Yield of Transbronchial Needle Aspiration During Mediastinal Lymph Node Sampling： Systematic Review and Meta-Analysis [J]. Chest， 2018，153（4）：929-938.
[17] ■imon M，Pop B，Toma IL，et al. The use of EBUS-TBNA and ROSE in the diagnosis of lung cancer [J]. Rom J Morphol Embryol，2017，58（1）：79-87.
[18] Gianella P，Soccal PM，Plojoux J，et al. Utility of Rapid On-Site Cytologic Evaluation during Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration in Malignant and Nonmalignant Disease [J]. Acta Cytol，2018，62（5-6）：380-385.
[19] Ravaioli S，Bravaccini S，Tumedei MM，et al. Easily detectable cytomorphological features to evaluate during ROSE for rapid lung cancer diagnosis：from cytology to histology [J]. Oncotarget，2017，8（7）：11　199-11　205.