|
|
|
| Value of MRI DWI combined with PI-RADS in screening prostate cancer |
| SHAN Lianqiang1 QU Sehua2 JIANG Xu3 YANG Xuezhen3 |
1.Department of Radiology, the Second Affiliated Hospital of Bengbu Medical College, Anhui Province, Bengbu 233040, China;
2.Department of Pediatrics, the First Affiliated Hospital of Bengbu Medical College, Anhui Province, Bengbu 233004, China;
3.Department of Urology, the Second Affiliated Hospital of Bengbu Medical College, Anhui Province, Bengbu 233040, China |
|
|
|
Abstract Objective To discuss the apparent diffusion coefficient (ADC) value of 1.5T magnetic resonance (MRI) combined with PI-RADS score in screening prostate cancer (PCa). Methods Forty patients with PCa were selected from December 2014 to September 2018 in the Second Affiliated Hospital of Bengbu Medical College, and as PCa group. At the same time, 60 patients with benign prostate were selected as benign group. The two groups were given 1.5T-MRI examination. The prostate imaging ADC value, eADC value and PI-RADS score of the two groups were compared, the diagnosis performance of PCa with different methods were compared. Results The PI-RADS score and eADC value in PCa group were higher than those in the benign group, while ADC value was lower than that in the benign group, the differences were highly statistically significant (P < 0.01). The ROC curve analysis showed that, the sensitivity, specificity and Youden index of ADC value combined with PI-RADS score in the diagnosis of PCa were significantly higher than the ADC and PI-RADS score alone, and the area under the curve of combined diagnosis was the biggest. Conclusion The ADC value of 1.5T-MRI combined with PI-RADS score can be used as a primary indicator of PCa screening. And it can effectively improve the screening effect of PCa, it is worth for clinical promotion and application.
|
|
|
|
|
|
[1] 黄亚强.于蛋白质组学的前列腺癌间质标记物筛选及MYL9表达的临床观察[D].广州：南方医科大学，2015.
[2] Heger Z，Cernei N，Gumulec J，et al. Determination of common urine substances as an assay for improving prostate carcinoma diagnostics [J]. Oncol Rep，2014，31（4）：846-854.
[3] Shiota M，Yokomizo A，Takeuchi A，et al. Co introduction of a steroid with docetaxel chemotherapy for metastatic castration resistant prostate cancer affects PSA flare [J]. BJU Int，2016，118（6）：880-884.
[4] Turkbey B，Choyke PL. Multiparametric MRI and prostate cancer diagnosis and risk stratification [J]. Curr Opin Urol，2012，22（4）：310-315.
[5] Roethke MC，Kuru TH，Schultze S，等.欧洲泌尿生殖放射学会PI-RADS评分系统在3.0T多参数前列腺MR成像中的应用价值：联合靶向MR/经直肠超声引导下前列腺活检[J].国际医学放射学杂志，2014，7（2）：95-96.
[6] 中华放射学杂志前列腺疾病诊疗工作组，中华放射学杂志编辑委员会.列腺病MR检查和检查共识[J].中华放射学杂志，2014，8（7）：531-534.
[7] Barentsz JQ，Richenberg J，Clements R，et al. ESUR prostate MR guideline 2012 [J]. Eur Radio，2012，22（4）：746-757.
[8] 张臻，左孟哲，王建良.基于PI-RADS v2评分的Mp-MRI联合PSAD对中高级别前列腺癌预测价值的分析[J].临床肿瘤学杂志，2017，22（11）：1012-1016.
[9] 叶靖，肖芹，山姆，等.高b值扩散加权成像鉴别前列腺中央腺体癌和良性增生结节[J].临床放射学杂志，2015， 34（6）：939-943.
[10] 顾伟光，赵文露，钱林清.DWI的ADC值在前列腺癌内分泌治疗后疗效评价中的应用[J].医学影像学杂志，2017， 27（12）：2357-2360.
[11] Hambrock T，Somford PM，Huisman HJ，et al. Relation-ship between apparent diffusion Coefficients at 3.0-T MR imaging and gleason grade in peripheral Zone prostate cancer [J]. Radiology，2011，259（2）：453-461.
[12] Barajas RF，Rubenstein JL，Chang JS，et al. Diffusion-weighted MR imaging derived apparent Diffusion-coefficient is predictive of clinical outcome in primary central nervous system lymphoma [J]. AJNR Am J Neuroradiol，2010，31（1）：60-66.
[13] 龚军伟.扩散张量成像和扩散加权成像在胶质瘤分级及鉴别诊断中的价值[D].重庆：重庆医科大学，2018.
[14] 马娟王，金英，王俭，等.磁共振扩散加权成像ADC、EADC脑泡型包虫病边缘带定量分析[J].新疆医科大学学报，2015，38（11）：1347-1350.
[15] 刘会佳，赵娓娓，任芳，等.DWI对前列腺癌疗效监测及ADC值与PSA相关性研究[J].放射学实践，2014，29（5）：487-490.
[16] 温淑蓉.ADC直方图分析法鉴别中央带前列腺癌与T2WI低信号增生结节的研究[J].放射学实践，2016， 31（11）：1076-1079.
[17] 刘莉，吴宁，欧阳汉，等.DWI在前列腺癌放疗疗效评估中的价值[J].放射学实践，2014，29（1）：77-80.
[18] 李艳君，冯彦景，查月芳，等.10g单丝在糖尿病周围神经病变筛查中的价值[J].河北医科大学学报，2015，36（8）：884-886.
[19] 肖莉，赵迎忠.经阴道三维超声联合二维超声对子宫肌瘤的诊断价值的临床研究[J].航空航天医学杂志，2018， 29（12）：1454-1456. |
|
|
|
