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Clinical effect of Qushi Jianfa Decoction combined with plum-blossom needle acupuncture in the treatment of alopecia seborrheica with syndrome of dampness stagnancy due to spleen deficiency |
ZHANG Xuesong1 ZHOU Dongmei2 |
1.Department of Dermatology, Shunyi Hospital of Beijing Traditional Chinese Medicine Hospital, Beijing 101300, China;
2.Department of Dermatology, Beijing Traditional Chinese Medicine Hospital, Capital Medical University, Beijing 100010, China |
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Abstract Objective To explore the clinical efficacy of Qushi Jianfa Decoction combined with plum-blossom needle in the treatment of alopecia seborrheica with syndrome of dampness stagnancy due to spleen deficiency. Methods Ninety patients with seborrheic alopecia admitted to Shunyi Hospital of Beijing Traditional Chinese Medicine Hospital from July 2016 to January 2018 were divided into control group (45 cases) and research group (45 cases) by random number table method. The patients in the control group were treated with conventional treatment, while the patients in the research group were treated with Qushi Jianfa Decoction combined with plum-blossom needle puncture on the basis of the control group. The two groups were treated continuously for 6 months. The clinical total effective rate, the Chinese medicine syndrome scores before and after treatment, the element levels of iron (Fe), calcium (Ca), zine (Zn) and copper (Cu) in the hair and recurrence rate of two groups were compared. Results The total effective rate of research group was significantly higher than that of the control group, the difference was statistically significant (P < 0.05). After treatment, the Chinese medicine syndrome scores of pruritus, greasy, hair loss and scaly in the research group were significantly lower than those in the control group, and the scores of the two groups were significantly lower than those before treatment, the differences were statistically significantly (P < 0.05 or P < 0.01). After treatment, the levels of Fe, Ca, Zn and Cu in the hair in the research group were significantly higher than those in the control group, and the levels of elements after treatment in the two groups were significantly higher than those before treatment, the differences were statistically significant (P < 0.05 or P < 0.01). During the follow-up period, the recurrence rate of the research group was significantly lower than that of the control group, the difference was statistically significant (P < 0.05). Conclusion The clinical curative effect of Qushi Jianfa Decoction combined with plum-blossom needle in the treatment of alopecia seborrhoeica with syndrome of dampness stagnancy due to spleen deficiency is significant, which can significantly improve symptoms, increase the level of trace elements in hair, and has a low recurrence rate.
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[1] 巫珊,张海州.脂溢性脱发的发生机制及治疗研究进展[J].日用化学品科学,2012,35(2):29-33.
[2] 黎伟珍,魏跃钢.脂溢性脱发的中西医研究进展[J].现代中西医结合杂志,2004,13(20):2786-2787.
[3] 赵致然,陈志强,王生隆,等.脂溢性脱发的机制和药物治疗进展[J].西北药学杂志,2016,31(4):440-442.
[4] 李勇,刘靖,李东海,等.补肾生发方联合非那雄胺治疗脂溢性脱发临床疗效分析[J].世界中西医结合杂志,2014, 9(8):862-863,912.
[5] 马倩,王学岭.脂溢性脱发的中医研究概况[J].中医临床研究,2016,8(15):105-107.
[6] 童涛,刘涛峰.中医药治疗脂溢性脱发的研究进展[J].湖南中医杂志,2014,30(10):186-187.
[7] 王和平,李玲玉,王姗姗,等.祛湿健发饮治疗脂溢性脱发的临床观察[J].中医药信息,2012,29(4):111-112.
[8] 蒋丽霞,李思念,张娜.梅花针叩刺与西药结合治疗男性雄激素源性脱发的临床研究[J].广州中医药大学学报,2016,33(4):498-501.
[9] 赵辨.临床皮肤病学[M].3版.南京:江苏科学技术出版社,2001:945-947.
[10] 许鹏光.中西医临床皮肤性病学[M].北京:中国医药科技出版社,2012:236-239.
[11] 国家中医药管理局.中药新药临床研究指导原则[S].北京:中国医药科技出版社,2002:134-135.
[12] 范瑞强,邓丙戌,杨志波.中医皮肤性病学[M].北京:科学技术文献出版社,2010:618-621.
[13] 廖金凤,段西凌.雄激素性脱发的病因病机[J].临床合理用药杂志,2013,6(14):174-176.
[14] 陈洁玲,江光明.脂溢性脱发的病因、诊断与治疗[J].临床医学工程,2013,20(6):692-693.
[15] 田河林,赵如同,苏县辉.非那雄胺药理作用研究新进展[J].中国药房,2008,19(34):2707-2709.
[16] 陈亮,王玎,祁坤明,等.中医综合疗法治疗脂溢性脱发探析[J].亚太传统医药,2016,12(18):108-109.
[17] 陈志光,李佩远,李宝英.18味除脂生发丸治疗油性脂溢性脱发34例临床观察[J].湖南中医杂志,2016,32(6):76-77.
[18] 王惠英,胡新华.自拟加味桑乌二四汤治疗脂溢性脱发46例[J].广西中医药,2018,41(2):25-26.
[19] 徐宜厚.徐宜厚皮肤病用药心得十讲[M].北京:中国医药科技出版社,2013:242.
[20] 陈蕾,毛健,张予晋.梅花针叩刺治疗脂溢性脱发的Meta分析[J].湖南中医杂志,2018,34(4):130-178.
[21] 张榆.复方黄柏液联合萆薢渗湿汤对脂溢性脱发(脾胃湿热证)头皮油脂分泌的影响[D].成都:成都中医药大学,2015.
[22] 罗文霞,贝宏,刘品梅.梅花针叩刺加擦姜汁治疗脂溢性脱发[J].临床医学,2016,36(5):121-122.
[23] 王艳,张倩影.祛脂生发饮联合非那雄胺治疗脾胃湿热型脂溢性脱发疗效及对发中微量元素水平的影响[J].现代中西医结合杂志,2018,27(12):1338-1340. |
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